Transcript errors generate a continuous stream of amyloid and prion-like proteins in human cells
Claire S. Chung, Yi Kou, Sarah J. Shemtov, Bert M. Verheijen, Ilse Flores, Kayla Love, Ashley Del Dosso, Max Andrew Thorwald, Yuchen Liu, Renaldo G. Toney, Lucy Carrillo, Megan M. Nguyen, Biao Huang, Yuxin Jin, Ashley Michelle Jauregui, , Marc Vermulst
The paper shows transcript errors generate amyloid and prion-like proteins in human cells, linking DNA damage to aging and disease.
bioRxiv · May 11, 2023 · PreprintMolecular Biology