Author

C. Arenz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

C. LEYRAT· 2 shared R. D. Healey· 2 shared S. Basu· 2 shared S. Granier· 2 shared A. Gupta· 1 shared C. BECHARA· 1 shared C. M. Grison· 1 shared D. Maurel· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

C. LEYRAT

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Expression of Plasmodium Major Facilitator Superfamily Protein in Transporters-Delta Candida Identifies a Drug Transporter

P. Maurya, M. Kumar, R. Jain, H. Singh, H. Thaer Abdulhameed Almuqdadi, A. Gupta, C. Arenz, N. Gaur, S. Singh

The paper assesses the functional relevance of a Plasmodium MFS protein as a drug transporter using Candida glabrata, showing antifungal resistance and antimalarial properties.

bioRxiv · Feb 18, 2024Cell Biology

Discovery and mechanism of action of small molecule inhibitors of ceramidases

S. Granier, R. D. Healey, E. Saied, X. Cong, G. Karsai, L. Gabellier, J. Saint-Paul, E. Del Nero, S. Jeannot, M. Drapeau, S. Fontanel, D. Maurel, S. Basu, C. LEYRAT, G. Bossis, , C. Arenz

The paper discovers small molecule inhibitors of alkaline ceramidase 3 using fluorescent substrates and characterizes their mechanism of action.

bioRxiv · Jun 15, 2021Biochemistry

BRED: bioluminescence energy transfer to dye for monitoring ceramide trafficking in cell

G. Naseri, C. Arenz

The paper introduces BRED, a bioluminescence resonance energy transfer system to monitor ceramide trafficking, demonstrating its application in tracking ceramide movement to the Golgi using flow cytometry.

bioRxiv · Mar 31, 2021 · PreprintBiochemistry

Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy

I. Vasiliauskaite - Brooks, R. D. Healey, P. Rochaix, R. Sounier, C. M. Grison, T. Waltrich - Augusto, M. Fortier, F. Hoh, E. M. Saied, C. Arenz, S. Basu, C. Leyrat, S. Granier

The paper reports the crystal structure of human ACER3, revealing its intramembrane architecture and explaining Ca2+ and Zn2+ regulation of its enzymatic activity and dysfunction in leukodystrophy.

bioRxiv · Jun 15, 2018Biochemistry