Author

C. E. Chitnis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Assay:proteomics· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 2 Organism:mouse· 1 Organism:plant (other)· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Huon· 3 shared E. Takashima· 2 shared I. Mueller· 2 shared J. Healer· 2 shared J. Sattabongkot· 2 shared M. Harbers· 2 shared R. J. Longley· 2 shared T. Tsuboi· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

C. Huon

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Evaluation of Precision of the Plasmodium knowlesi Growth Inhibition Assay for Plasmodium vivax Duffy-Binding Protein-based Malaria Vaccine Development

J. E. Mertens, C. A. Rigby, M. Bardelli, D. Quinkert, M. M. Hou, A. Diouf, S. E. Silk, C. E. Chitnis, A. M. Minassian, R. W. Moon, C. A. Long, S. J. Draper, K. Miura

This study evaluates the precision of the Plasmodium knowlesi growth inhibition assay for Plasmodium vivax Duffy-binding protein-based malaria vaccine development, finding significant assay-to-assay variation in %GIA and GIA50.

bioRxiv · Jan 23, 2024Immunology

Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target

M. P. Wagner, P. Formaglio, O. Gorgette, J. M. Dziekan, C. Huon, I. Berneburg, S. Rahlfs, J.-C. Barale, S. I. Feinstein, A. B. Fisher, D. Menard, Z. Bozdech, R. Amino, L. Touqui, C. E. Chitnis

This study shows that human PRDX6 is essential for malaria parasite survival by repairing lipid peroxidation damage and that inhibiting it can kill parasites, including artemisinin-resistant strains.

bioRxiv · Apr 11, 2022Cell Biology

Naturally acquired antibody kinetics against Plasmodium vivax antigens in people from a low malaria transmission region in western Thailand

Z. S.-J. Liu, J. Sattabongkot, M. White, S. Chotirat, C. Kumpitak, E. Takashima, M. Harbers, W.-H. Tham, J. Healer, C. E. Chitnis, T. Tsuboi, I. Mueller, R. J. Longley

This study tracks antibody kinetics against Plasmodium vivax antigens in individuals from a low-transmission region, showing long-lived IgG responses and IgM variability.

bioRxiv · Oct 21, 2021Microbiology

Plasmodium falciparum and helminth coinfections increase IgE and parasite-specific IgG responses

R. Santano, R. Rubio, B. Grau-Pujol, V. Escola, O. Muchisse, I. Cuamba, M. Vidal, P. Cistero, G. Ruiz-Olalla, R. Aguilar, M. Demontis, J. C. Jamine, A. Cossa, C. Sacoor, J. Cano, , C. Dobano

This study examines how co-infections with Plasmodium falciparum and helminths affect antibody responses in Mozambican individuals, finding increased IgE and IgG levels in co-infected individuals.

bioRxiv · May 26, 2021Immunology

Phosphorylation Dependent Assembly of a 14-3-3 Mediated Signaling Complex During Red Blood Cell Invasion by Plasmodium falciparum Merozoites

K. R. More, I. Kaur, Q. Giai Gianetto, B. M. Invergo, T. Chaze, R. Jain, C. Huon, P. Gutenbrunner, H. Weisser, M. Matondo, J. S. Chaudhary, G. Langsley, S. Singh, C. E. Chitnis

mBio · Aug 25, 2020Peer-reviewedMicrobiology

Development and validation of serological markers for detecting recent exposure to Plasmodium vivax infection

R. J. Longley, M. T. White, E. Takashima, J. Brewster, M. Morita, M. Harbers, L. J. Robinson, F. Matsuura, S.-J. Liu, C. S. N. Li-Wai-Suen, W.-H. Tham, J. Healer, C. Huon, C. E. Chitnis, W. Nguitragool, , I. Mueller

The paper identifies and validates a panel of 8 P. vivax proteins whose IgG antibody responses can detect recent exposure to P. vivax infections within the prior 9 months with 80% sensitivity and specificity.

bioRxiv · Nov 30, 2018 · PreprintMicrobiology