C. Gauthier

A single domain intrabody targeting the follicle-stimulating hormone receptor (FSHR) impacts FSH-induced G protein-dependent signalling

The paper characterizes an intrabody that modulates FSHR signaling by reducing cAMP production without affecting Gs recruitment.

Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response

This paper shows that displaying GM3g glycans on proteins using specific chemical linkers elicits strong, germline-encoded B cell responses that do not undergo affinity maturation.

The bacterial virulence factors rhamnolipids and their (R)-3-hydroxyalkanoate precursors activate Arabidopsis innate immunity through two independent mechanisms

This paper shows that rhamnolipids and their (R)-3-hydroxyalkanoate precursors activate Arabidopsis immunity through two distinct mechanisms involving different receptors and signaling pathways.

Burkholderia thailandensis methylated hydroxy-alkylquinolines: biosynthesis and antimicrobial activity in co-culture experiments

This study identifies N-oxidated methyl-alkenylquinolines (HMAQ-NOs) as antimicrobial compounds produced by Burkholderia thailandensis, showing they are 50-fold more active than their non-oxidized counterparts against Bacillus subtilis.

Modulation of bacterial multicellularity via spatiotemporal polysaccharide secretion

The paper shows that Myxococcus xanthus uses temporally and spatially controlled polysaccharide secretion to coordinate multicellular behaviors like swarm migration and biofilm formation.