Author

R. A. Russell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Immunology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

E. Sezgin· 2 shared L. P. Deimel· 2 shared Q. J. Sattentau· 2 shared X. Xue· 2 shared A. Ferrari· 1 shared A. H. Bedard· 1 shared A. J. Baldwin· 1 shared A. Khan· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

E. Sezgin

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Author profile →

5 papers

Recent·Most cited

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis

L. Z. Drexhage, S. Zhang, M. DuPont, F. Ragaller, E. Sjule, J. C. Caballero, L. P. Deimel, H. Robertson, R. A. Russell, O. Dushek, E. Sezgin, N. Karaji, Q. J. Sattentau

The paper shows that ADAM10-mediated removal of mucins during T cell apoptosis enhances macrophage efferocytosis.

bioRxiv · Aug 22, 2023Cell Biology

Aster-dependent non-vesicular transport facilitates dietary cholesterol uptake

A. Ferrari, E. Whang, X. Xiao, J. P. Kennelly, B. Romartinez- Alonso, J. J. Mack, T. Weston, K. Chen, Y. Kim, M. Tol, L. Bideyan, A. Nguyen, Y. Gao, L. Cui, A. H. Bedard, , P. Tontonoz

The paper identifies the Aster pathway as critical for dietary cholesterol uptake and shows it can be targeted with a small molecule inhibitor.

bioRxiv · Jul 7, 2023 · PreprintPhysiology

Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response

L. P. Deimel, X. Xue, A. Khan, L. Moynie, C. J. Buchanan, G. Sun, R. McBride, H. Schuster, C. Gauthier, R. Saliba, K. Leonavicius, L. Minall, G. Bort, R. A. Russell, E. Sezgin, , Q. J. Sattentau

This paper shows that displaying GM3g glycans on proteins using specific chemical linkers elicits strong, germline-encoded B cell responses that do not undergo affinity maturation.

bioRxiv · Jun 3, 2023 · PreprintImmunology

Strikingly different roles of SARS-CoV-2 fusion peptides uncovered by neutron scattering

A. Santamaria, K. C. Batchu, O. Matsarskaia, S. F. Prevost, D. Russo, F. Natali, T. Seydel, I. Hoffmann, V. Laux, M. Haertlein, T. A. Darwish, R. A. Russell, G. Corucci, G. Fragneto, A. Maestro, N. R. Zaccai

This study uses neutron scattering to reveal how calcium and cholesterol influence the SARS-CoV-2 Spike protein's role in membrane fusion during viral entry.

bioRxiv · Aug 30, 2021Biophysics

Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques

K. R. Bewley, K. E. R. Gooch, K. M. Thomas, S. R. Longet, N. Wiblin, L. Hunter, K. Chan, P. Brown, R. A. Russell, C. Ho, G. Slack, H. E. Humphries, L. Alden, L. Allen, M. Aram, , M. Carroll

This study evaluates vaccine-enhanced disease in ferrets and rhesus macaques after formalin-inactivated SARS-CoV-2 vaccination, finding mild transient lung pathology but no significant enhancement.

bioRxiv · Dec 21, 2020Pathology