Author

C. Massey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Research Focus:ecology & biodiversity· 1 Organism:human· 1

Frequent Co-Authors

J. E. Comer· 2 shared A. Carston· 1 shared A. Drelich· 1 shared A. J. Cluff· 1 shared A. LeBeau· 1 shared A. Morrison· 1 shared A. N. Freiberg· 1 shared A. Odle· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersImmunology

J. E. Comer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Humidity determines penetrance of a latitudinal gradient in genetic selection on the microbiota by Drosophila melanogaster

C. Massey, M. E. Nosker, J. Gale, S. Scott, C. J. Walker, A. J. Cluff, S. Wilcox, A. Morrison, S. J. G. Morgan, J. Beltz, P. Schmidt, J. Chaston

This study shows that humidity influences the genetic selection on microbiota in Drosophila melanogaster, with variation in microbiota composition linked to latitude and environmental conditions.

bioRxiv · May 2, 2024 · PreprintMicrobiology

Profound immunomodulatory effects of 225Ac-NM600 drive enhanced anti-tumor responsein prostate cancer

C. de Aguiar Ferreira, H. K. Potluri, C. Massey, J. J. Grudzinski, A. Carston, N. Clemons, A. S. Thickens, Z. Rosenkrans, C. Choi, A. Pinchuk, O. Kwon, J. J. Jeffery, B. Bednarz, Z. Morris, J. Weichert, , R. Hernandez

This study shows that 225Ac-NM600, an alpha-emitting radiopharmaceutical, enhances anti-tumor responses in prostate cancer by modulating the immune microenvironment.

bioRxiv · Sep 26, 2022 · PreprintImmunology

A synthetic peptide CTL vaccine targeting nucleocapsid confers protection from SARS-CoV-2 challenge in rhesus macaques

P. Harris, T. Brasel, C. Massey, C. Herst, S. Burkholz, P. Lloyd, T. Blankenberg, T. Bey, R. Carback, T. Hodge, S. Ciotlos, L. Wang, J. E. Comer, R. M. Rubsamen

A synthetic peptide vaccine targeting SARS-CoV-2 nucleocapsid protein protected rhesus macaques from viral challenge, reducing pneumonia and viral load.

bioRxiv · Apr 24, 2021Immunology

The Development of a Novel Nanobody Therapeutic for SARS-CoV-2

G. Ye, J. Gallant, C. Massey, K. Shi, W. Tai, J. Zheng, A. Odle, M. Vickers, J. Shang, Y. Wan, A. Drelich, K. Kempaiah, V. Tat, S. Perlman, L. Du, , F. Li

This paper develops a potent, low-cost nanobody therapeutic, Nanosota-1C-Fc, that effectively blocks SARS-CoV-2 infection in vitro and in vivo with high affinity and stability.

bioRxiv · Nov 17, 2020Microbiology

Pyronaridine Tetraphosphate Efficacy Against Ebola Virus Infection in Guinea Pig

T. R. Lane, C. Massey, J. E. Comer, A. N. Freiberg, H. Zhou, J. Dyall, M. Holbrook, M. Anantpadma, R. A. Davey, P. Madrid, S. Ekins

This paper evaluates pyronaridine tetraphosphate's efficacy against Ebola and Marburg viruses in guinea pigs, showing 40% survival and suggesting its potential for antiviral repurposing.

bioRxiv · Mar 20, 2020Pharmacology & Toxicology