Author

W. Tai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

G. Cheng· 2 shared J. Ma· 2 shared L. Du· 2 shared M. Tian· 2 shared S. Feng· 2 shared Z. Yang· 2 shared A. Drelich· 1 shared A. LeBeau· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

G. Cheng

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

An Efficient and Safe Trans-complementation System for MPXV Mimicking Authentic Viral Infection

J. Liu, L. Zhu, L. Mei, Y. Liu, Y. Qu, Y. Yuan, F. Zhang, Y. Cao, Y. Zhu, W. Tai, J. Ma, M. Zheng, X. Shi, Y. Liu, G. Cheng

This paper develops a safe trans-complementation system for MPXV that mimics authentic infection, enabling research in lower biosafety labs without live virus.

bioRxiv · Dec 29, 2023 · PreprintMicrobiology

Development of a ferritin-based nanoparticle vaccine against the SARS-CoV-2 Omicron variant

W. Tai, B. Chai, S. Feng, X. Zhuang, J. Ma, M. Pang, L. Pan, Z. Yang, M. Tian, G. Cheng

This paper develops a ferritin-based nanoparticle vaccine targeting the SARS-CoV-2 Omicron variant, showing enhanced immunogenicity compared to a non-nanoparticle version.

bioRxiv · Mar 13, 2022Microbiology

Infection and chronic disease activate a brain-muscle signaling axis that regulates muscle performance

S. Yang, M. Tian, Y. Dai, S. Feng, Y. Wang, D. Chhangani, T. Ou, W. Li, Z. Yang, J. McAdow, D. Rincon-Limas, X. Yin, W. Tai, G. Chen, A. N. Johnson

This study identifies a brain-muscle signaling axis activated by infections and chronic diseases that reduces muscle performance through cytokine-dependent mechanisms.

bioRxiv · Dec 20, 2020Immunology

The Development of a Novel Nanobody Therapeutic for SARS-CoV-2

G. Ye, J. Gallant, C. Massey, K. Shi, W. Tai, J. Zheng, A. Odle, M. Vickers, J. Shang, Y. Wan, A. Drelich, K. Kempaiah, V. Tat, S. Perlman, L. Du, , F. Li

This paper develops a potent, low-cost nanobody therapeutic, Nanosota-1C-Fc, that effectively blocks SARS-CoV-2 infection in vitro and in vivo with high affinity and stability.

bioRxiv · Nov 17, 2020Microbiology

Biomechanical Characterization of SARS-CoV-2 Spike RBD and Human ACE2 Protein-Protein Interaction

W. Cao, C. Dong, S. Kim, D. Hou, W. Tai, L. Du, W. Im, X. F. Zhang

This study quantifies the biophysical differences in SARS-CoV-2 and SARS-CoV-1 RBD-ACE2 interactions using single-molecule force spectroscopy and SMD simulations, revealing a key N-glycan interaction in SARS-CoV-2 that enhances binding affinity.

bioRxiv · Jul 31, 2020Biophysics