C. Peterson

Sex differences in plasma, adipose tissue, and central accumulation of cannabinoids, and behavioural effects of oral cannabis consumption in male and female C57BL/6 mice.

This study examines sex differences in cannabinoid accumulation and behavioural effects of oral cannabis in mice, finding delayed pharmacokinetics and sex-specific behavioural responses.

Cryo-EM structure of the human Sirtuin 6-nucleosome complex

The paper presents the cryo-EM structure of the human SIRT6-nucleosome complex, revealing how SIRT6 deacetylates histone H3 K9 and K56.

Cellular and Fibrillar Collagen Analyses in an Animal Model of Retinal Detachment-Related Proliferative Vitreoretinopathy Reveals a Defined Transition to Chronic Fibrosis

This study uses a rabbit model of retinal detachment to analyze cellular and fibrillar collagen changes, revealing a transition to chronic fibrosis in PVR.

Local adaptation and host specificity to copepod intermediate hosts by the Schistocephalus solidus tapeworm

The paper tests if the tapeworm Schistocephalus solidus is locally adapted and host specific to copepod intermediate hosts, finding no local adaptation but host specificity between copepod genera.

Single-cell RNA Sequencing Reveals Immunosuppressive Myeloid Cell Diversity and Restricted Cytotoxic Effector Cell Trafficking and Activation During Malignant Progression in Glioma

This study uses single-cell RNA sequencing to analyze immune cell changes during glioma progression, identifying immunosuppressive myeloid cell subsets and potential therapeutic targets.

Performance Determinants of Unsupervised Clustering Methods for Microbiome Data

The paper evaluates clustering methods for microbiome data, identifies scenarios where specific metrics underperform, and proposes a combined metric that improves performance across datasets.

A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein

The paper reports the high-resolution structure of the SARS-CoV-2 Spike RBD and identifies a conserved epitope accessible in open conformations, which is targeted by cross-reactive antibodies.

Specialization for cell-free or cell-to-cell spread of BAC-cloned HCMV strains is determined by factors beyond the UL128-131 and RL13 loci.

This study shows HCMV strains can specialize in cell-free or cell-to-cell spread, with these traits determined by factors beyond the UL128-131 and RL13 loci.

OCTAVVS: A graphical toolbox for high-throughput preprocessing and analysis of vibrational spectroscopy imaging data

OCTAVVS provides a graphical toolbox for preprocessing and analyzing vibrational spectroscopy imaging data, including atmospheric correction and clustering.

Depletion of resident muscle stem cells inhibits muscle fiber hypertrophy induced by lifelong physical activity

This study shows that satellite cell depletion limits muscle fiber hypertrophy in response to lifelong physical activity, with muscle type-specific effects on growth mechanisms.

Characterization of expression quantitative trait loci in extensively phenotyped pedigrees ascertained for bipolar disorder

The paper characterizes expression quantitative trait loci (eQTL) in bipolar disorder pedigrees to understand genetic regulation and heritability.