Author

C.-L. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. R. Daniel· 3 shared D. G. Kirsch· 3 shared L. Luo· 3 shared S. Hasapis· 2 shared Y. Ma· 2 shared Z. Li· 2 shared A. Ayyaz· 1 shared A. B. Sibley· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

A. R. Daniel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

p53 promotes revival stem cells in the regenerating intestine after severe radiation injury

C. Morral, A. Ayyaz, H.-C. Kuo, M. Fink, I. Verginadis, A. R. Daniel, D. N. Burner, L. M. Driver, S. Satow, S. Hasapis, R. Ghinnagow, L. Luo, Y. Ma, L. D. Attardi, C. Koumenis, , D. G. Kirsch

bioRxiv · Apr 27, 2023Cell Biology

Human Early Syncytiotrophoblasts Are Highly Susceptible to SARS-CoV-2 Infection

P. Liu, D. RUAN, Z.-W. Ye, S. Yuan, Z. Li, W. Zhang, C. P. Ong, K. Tang, J. Guo, Y. Xuan, T. T. K. K. Tam, Y. Huang, Q. Zhang, C.-L. Lee, P. C. N. Chiu, , D.-Y. Jin

This paper shows that human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infection via ACE2 and demonstrates antiviral efficacy of remdesivir and GC376.

bioRxiv · Nov 17, 2022Cell Biology

Temporary knockdown of p53 during focal limb irradiation increases the development of sarcomas

A. R. Daniel, C.-L. Lee, C. Su, N. T. Williams, Z. Li, J. Huang, O. Lopez, L. Luo, Y. Ma, L. D. S. Campos, S. R. Selitsky, J. L. Modliszewski, S. Liu, Y. M. Mowery, D. M. Cardona, D. G. Kirsch

This study shows that temporarily knocking down p53 during radiation therapy increases the risk of sarcoma development in mice.

bioRxiv · Oct 28, 2022Cancer Biology

Activation of Notch1 drives the development of radiation-induced thymic lymphoma in p53 wild-type mice

C.-L. Lee, K. D. Brock, S. Hasapis, D. Zhang, A. B. Sibley, X. Qin, J. Gresham, I. Caraballo, L. Luo, A. R. Daniel, M. J. Hilton, K. Owzar, D. G. Kirsch

This study identifies Notch1 activation as a key driver of radiation-induced thymic lymphoma in p53 wild-type mice through genomic and functional analyses.

bioRxiv · Aug 21, 2020 · PreprintCancer Biology

Photon-counting cine-cardiac CT in the mouse

D. P. Clark, M. Holbrook, C.-L. Lee, C. T. Badea

This paper demonstrates 4D photon-counting detector CT in a mouse atherosclerosis model, achieving high-fidelity spectral and material information with reduced noise and improved resolution.

bioRxiv · Jun 4, 2019Bioengineering