Author

Chai-wan Kim

The University of Texas Southwestern Medical CenterPrimary ORCID profile (0000-0001-5105-2829 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Chai-Wan KimiD1 paper · Stanford Medicine

Biology Disciplines

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Cell Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jay D. HortoniD· 2 shared Xiaorong FuiD· 2 shared Chalermchai KhemtongiD· 1 shared Chao LiiD· 1 shared Chongshan DaiiD· 1 shared Craig R. MalloyiD· 1 shared Gaurav SharmaiD· 1 shared Goncalo Dias do ValeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Jay D. HortonORCID

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2 papers

Recent·Most cited

Unrestrained fatty acid oxidation triggers heart failure in mice via cardiolipin loss and mitochondrial dysfunction

Chai-wan Kim, Goncalo Dias do Vale, Xiaorong Fu, Jeffrey G. McDonald, Chongshan Dai, Chao Li, Zhao V. Wang, Gaurav Sharma, Chalermchai Khemtong, Craig R. Malloy, Stanisław Deja, Shawn C. Burgess, Matthew A. Mitsche, Jay D. Horton

This study shows that excessive fatty acid oxidation in mice leads to heart failure through cardiolipin loss and mitochondrial dysfunction, suggesting that increasing FAO may be harmful in heart failure.

Journal of Clinical Investigation · Apr 30, 2026Peer-reviewedCell Biology

Identification and Regulation of a Hepatic Lipogenic Metabolon

Xiaotong Zhu, William Bennion McKean, Tam Tran, Xiaorong Fu, Jay D. Horton, Chai-Wan Kim

The paper identifies a hepatic lipogenic metabolon that enhances fatty acid and triglyceride synthesis through post-translational regulation, suggesting it as a therapeutic target for metabolic liver diseases.

bioRxiv · Jan 5, 2026 · PreprintCell Biology