Author

Christy Biji

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexandra E. GouldiD· 1 shared Ana Geller· 1 shared Ananthan SadagopaniD· 1 shared Antia Valle-TojeiroiD· 1 shared Benjamin Jacob DrapkiniD· 1 shared Beth StevensiD· 1 shared Bingchen LiiD· 1 shared Cary N. WeissiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alexandra E. GouldORCID

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2 papers

Recent·Most cited

The G-protein coupled receptor GPR34 maintains the homeostatic state of microglia and restrains the disease-associated microglial response in an Alzheimers disease model

Ana Geller, Min Jee Kwon, Sean Simmons, Qihong Xu, William E. Martenis, Jordan L. Doman, Sahana Natarajan, Katherine J. Stalnaker, Jixiang Zhang, Xian Adiconis, Trang Nguyen, Matthew Demers, Donovan L. Batzli, Antia Valle-Tojeiro, Christy Biji, , Prabhat S. Kunwar

This study shows that GPR34 maintains microglial homeostasis and limits disease-associated microglial responses in Alzheimer's disease models.

bioRxiv · Nov 26, 2025 · PreprintNeuroscience

Cancer target discovery enabled by transcriptome-based virtual CRISPR screening

Ananthan Sadagopan, Bingchen Li, Jiao Li, Yantong Cui, Riva Deodhar, Di Yang, Yifan Wu, Prathyusha Konda, Christy Biji, Dharma R. Thapa, Meha Thakur, Cary N. Weiss, Toni K. Choueiri, Jaimie H. Cheah, John G. Doench, , Srinivas Raghavan Viswanathan

This study uses machine learning to infer gene dependencies from tumor transcriptomes, identifying cancer vulnerabilities in rare cancers without experimental screening.

bioRxiv · Oct 24, 2024 · PreprintCancer Biology