Author

Donovan L. Batzli

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Steven A. CarriD· 2 shared Alexandra E. GouldiD· 1 shared Ana Geller· 1 shared Anna Goldstein· 1 shared Antia Valle-TojeiroiD· 1 shared Beth StevensiD· 1 shared Blanche C. IpiD· 1 shared Christian Taeger· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Steven A. CarrORCID

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2 papers

Recent·Most cited

The G-protein coupled receptor GPR34 maintains the homeostatic state of microglia and restrains the disease-associated microglial response in an Alzheimers disease model

Ana Geller, Min Jee Kwon, Sean Simmons, Qihong Xu, William E. Martenis, Jordan L. Doman, Sahana Natarajan, Katherine J. Stalnaker, Jixiang Zhang, Xian Adiconis, Trang Nguyen, Matthew Demers, Donovan L. Batzli, Antia Valle-Tojeiro, Christy Biji, , Prabhat S. Kunwar

This study shows that GPR34 maintains microglial homeostasis and limits disease-associated microglial responses in Alzheimer's disease models.

bioRxiv · Nov 26, 2025 · PreprintNeuroscience

Discovery of chromatin-based determinants of azacytidine and decitabine anti-cancer activity

Rishi V. Puram, Qiangzong Yin, YuhJong Liu, Justine C. Rutter, Daniel P. Bondeson, Maria C. Saberi, Lisa A. Miller, Michael Yifei Du, Khanh Nguyen, Donovan L. Batzli, Hilina B. Woldemichael, Christian Taeger, Anna Goldstein, Ming Y. Chu, Qi Guo, , Todd R. Golub

This study identifies DNA hypomethylation, not DNA damage, as the primary mechanism of azacytidine and decitabine anti-cancer activity, linking it to chromatin regulators like USP48.

bioRxiv · Jul 29, 2025 · PreprintCancer Biology