Author

D. C. Young

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. B. Moody· 2 shared J. A. Mayfield· 2 shared A. D. Huang· 1 shared A. Muir· 1 shared B. Lindley· 1 shared C. Akusobi· 1 shared C. C. Aldrich· 1 shared D. Motooka· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

D. B. Moody

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Population Pharmacokinetics and Target Attainment Analysis of Vancomycin after Intermittent Dosing in Adults with Cystic Fibrosis

V. Yellepeddi, B. Lindley, E. Radetich, S. Kumar, Z. N. Bhakta, L. Leclair, M. Parrot, D. C. Young

This study develops a population pharmacokinetic model for vancomycin in adults with cystic fibrosis and evaluates dosing scenarios to achieve target drug exposure.

bioRxiv · Jul 28, 2023Pharmacology & Toxicology

Genetic and lipidomic identification of tuberculostearic acid as a controller of mycobacterial membrane compartmentalization

M. Prithviraj, T. Kado, J. A. Mayfield, D. C. Young, A. D. Huang, D. Motooka, S. Nakamura, M. S. Siegrist, D. B. Moody, Y. S. Morita

The paper identifies tuberculostearic acid (TBSA) as a key lipid controlled by the gene cfa, which regulates membrane compartmentalization in Mycobacterium smegmatis.

bioRxiv · Aug 17, 2022 · PreprintMicrobiology

Cell envelope remodeling requires high concentrations of biotin during Mycobacterium abscessus model lung infection

M. R. Sullivan, K. McGowen, Q. Liu, C. Akusobi, D. C. Young, J. A. Mayfield, S. Raman, I. D. Wolf, D. B. Moody, C. C. Aldrich, A. Muir, E. J. Rubin

This study identifies biotin-dependent fatty acid remodeling as essential for Mycobacterium abscessus survival in the lung, suggesting biotin synthesis and fatty acid metabolism as therapeutic targets.

bioRxiv · Jul 20, 2022 · PreprintMicrobiology