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37 papers
Recent·Most cited
Q. Gao, L. Bao, H. Mao, L. Wang, K. Xu, m. Yang, Y. Li, L. Zhu, N. Wang, Z. Lv, H. Gao, X. Ge, B. Kan, Y. Hu, J. Liu, , C. Qin
A purified inactivated SARS-CoV-2 vaccine candidate (PiCoVacc) induces neutralizing antibodies in animals and shows safety and partial to complete protection against SARS-CoV-2 strains.
bioRxiv · Apr 17, 2020Microbiology
G. Ali, R. Zhao, M. Zhang, K. G. Jain, J. Chang, S. Komatsu, X. Fang, B. Zhou, J. Liang, D. Jiang, M. Ikebe, M. A. Matthay, H.-L. Ji
This study shows that the fibrinolytic niche regulates alveolar type 2 cell function and regeneration through the uPA-A6-CD44-ENaC cascade, with implications for lung injury repair.
bioRxiv · Mar 24, 2020 · PreprintCell Biology
The paper shows that patterns of fly wing evolution can be explained by a neutral model with mutational pleiotropy, refuting a previous claim of a linear correlation between mutational variance and evolutionary divergence.
bioRxiv · Feb 18, 2020Evolutionary Biology
C. Yao, X. Guan, G. Carraro, T. Parimon, X. Liu, G. Huang, H. Soukiasian, G. David, S. S. Weight, J. A. Belperio, P. Chen, D. Jiang, P. W. Noble, B. R. Stripp
This study shows that senescence of alveolar type 2 stem cells drives pulmonary fibrosis and that targeting p53 or Tgfβ can block fibrogenesis.
bioRxiv · Nov 18, 2019 · PreprintCell Biology
C. Warman, K. Panda, Z. Vejlupkova, S. Hokin, E. Unger-Wallace, R. A. Cole, A. M. Chettoor, D. Jiang, E. Vollbrecht, M. M. Evans, R. K. Slotkin, J. E. Fowler
This study identifies coordinated expression between highly expressed maize pollen genes and neighboring transposable elements, showing a link between transcript levels and pollen fitness.
bioRxiv · Oct 7, 2019Plant Biology
D. Jiang, J. Wang, X. Zhao, Y. Li, Q. Zhang, C. Song, H. Zeng, X. Wang
The paper reports a quadruple mutant of hepatitis B virus showing moderate resistance to tenofovir and demonstrates that combination therapy with entecavir and tenofovir effectively suppresses this resistant mutant.
bioRxiv · May 13, 2019Microbiology
J. Momand, P. Magdziarz, Y. Feng, D. Jiang, E. Parga, A. Celis, E. Denny, X. Wang, M. L. Phillips, E. Monterroso, S. E. Kane, F. Zhou
This study characterizes t-Darpp's structure, metal-binding, and phosphorylation by CDK1 and CDK5, revealing its monomeric form and calcium-binding properties.
bioRxiv · Jun 19, 2017Biochemistry