Author

V. Bankaitis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:yeast· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Tripathi· 3 shared Y. Wang· 2 shared A. Aggarwal· 1 shared A. Arunagiri· 1 shared A. Cazenave-Gassiot· 1 shared A. Ghosh· 1 shared A. H. Nile· 1 shared A. Laganowsky· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBiophysics

A. Tripathi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mechanisms by Which Small Molecule Inhibitors Arrest Sec14 Phosphatidylinositol Transfer Protein Activity

X. R. Chen, L. Poudel, Z. Hong, P. Johnen, S. S. Katti, A. Tripathi, A. H. Nile, S. M. Green, G. Schaaf, F. Bono, v. bankaitis, T. I. Igumenova

This study investigates how small molecule inhibitors affect Sec14 phosphatidylinositol transfer protein activity using structural analysis to inform antifungal drug design.

bioRxiv · Aug 1, 2022 · PreprintBiophysics

Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction

Y.-T. Yeh, C. Sona, X. Yan, A. Pathak, M. I. McDermott, Z. Xie, L. Liu, A. Arunagiri, Y. Wang, A. Cazenave-Gassiot, A. Ghosh, F. von Meyenn, S. Kumarasamy, S. M. Najjar, S. Jia, , M. N. Poy

The paper shows restoring PITPNA in T2D human islets reverses beta-cell dysfunction by improving insulin granule maturation and glucose-stimulated insulin secretion.

bioRxiv · Jul 6, 2022Cell Biology

A Sec14-like Phosphatidylinositol Transfer Protein Paralog Defines a Novel Class of Heme-binding Proteins With An Unusual Heme Coordination Mechanism

D. Khan, D. Lee, G. Gulten, A. Aggarwal, J. Wofford, K. V. Inna, A. Tripathi, J. W. Patrick, D. M. Eckert, A. Laganowsky, J. C. Sacchettini, P. Lindahl, V. Bankaitis

The paper identifies Sfh5 as a novel heme-binding protein with an unusual coordination mechanism, distinct from its Sec14-like PITP family members.

bioRxiv · Mar 19, 2020Biochemistry

Non-Canonical Regulation of Phosphatidylserine Metabolism by a Phosphatidylinositol Transfer Protein and a Phosphatidylinositol 4-OH Kinase

Y. Wang, P. Yuan, A. Tripathi, M. Rodriguez, M. Lonnfors, M. Eisenberg-Bord, M. Schuldiner, V. Bankaitis

The paper shows that Psd2-dependent phosphatidylethanomaine production in yeast relies on Psd2, Sfh4, and Stt4, with Sfh4 activating the pathway through a physical interaction rather than its PtdIns transfer activity.

bioRxiv · Jul 8, 2019Cell Biology