Author

Larissa Launhardt

University Medical Center of the Johannes Gutenberg University Mainz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Eliana StanganelloiD· 2 shared Alessandra GarganoiD· 1 shared Amina Othman· 1 shared Anna I. BrichkinaiD· 1 shared Ciarán McDonnelliD· 1 shared Dominique Hoch· 1 shared Fatma Aktuna· 1 shared Geoffroy AndrieuxiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Eliana StanganelloORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Loss of CD44 re-educates pancreatic cancer-associated fibroblasts modulating their fibrotic and immunosuppressive functions

Sven Máté Treffert, Yvonne M. Heneka, Julie Martin, Alessandra Gargano, Larissa Launhardt, Özlem Akilli‐Öztürk, Eliana Stanganello, Geoffroy Andrieux, Dominique Hoch, Steffen Joachim Sonnentag, Lisa-Marie Mehner, Leonel Muñoz‐Sagredo, Michelle Christ, Véronique Orian‐Rousseau

This study shows that CD44 deletion in pancreatic cancer-associated fibroblasts reduces tumor volume, alters their morphology and function, and enhances anti-tumor immune responses.

Cell Death and Disease · Aug 15, 2026Peer-reviewedCancer Biology

Tumor Cell Death Drives Tumor-Promoting IL-6+ iCAF formation via P2X7-activation

Ciarán McDonnell, Valeriya V. Zinina, Amina Othman, Larissa Launhardt, Anna I. Brichkina, Fatma Aktuna, Magdalena Brkic, Matthias Lauth, Eliana Stanganello, Mark R. Schmitt

The paper shows chemotherapy-induced ATP release from dying pancreatic cancer cells activates P2X7 in stellate cells, promoting IL-6 production and tumor resistance.

bioRxiv · Mar 20, 2026 · PreprintCancer Biology