Author

E. B. Rankin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. C. Koong· 1 shared A. J. Giaccia· 1 shared A. Kim· 1 shared A. M. Li· 1 shared A. N. Diep· 1 shared A. S. Yu· 1 shared B. He· 1 shared B. W. Loo· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. C. Koong

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3 papers

Recent·Most cited

Serine Starvation Silences Estrogen Receptor Signaling through Histone Hypoacetylation

A. M. Li, Y. Li, B. He, Y. Ramirez, H. Jiang, M.-N. Zhou, C. Lu, J. J. Gruber, E. B. Rankin, J. Ye

The paper shows serine starvation reduces ER expression and histone acetylation in breast cancer cells, linking metabolic stress to chromatin changes and ER pathway inactivation.

bioRxiv · Sep 5, 2021 · PreprintCancer Biology

Neutralizing PD-L1 and PD-L2 Enhances the Efficacy of Immune Checkpoint Inhibitors in Ovarian Cancer.

Y. R. Miao, K. N. Thakkar, J. Qian, M. S. Kariolis, W. Huang, S. A. Nandagopal, T. Yang, A. N. Diep, G. M. Cherf, Y. Xu, E. J. Moon, Y. Xiao, H. Alemany, T. Li, W. Yu, , A. J. Giaccia

The paper develops a high-affinity sPD-1 decoy molecule that neutralizes both PD-L1 and PD-L2, showing superior antitumor activity in ovarian cancer models compared to PD-1/PD-L1 antibodies.

bioRxiv · Jan 19, 2020 · PreprintCancer Biology

FLASH irradiation enhances the therapeutic index of abdominal radiotherapy for the treatment of ovarian cancer

K. Levy, S. Natarajan, J. Wang, S. Chow, J. T. Eggold, P. Loo, R. Manjappa, F. M. Lartey, E. Schüler, L. Skinner, M. Rafat, R. Ko, A. Kim, D. Al Rawi, R. von Eyben, , E. B. Rankin

This study shows FLASH irradiation reduces intestinal injury while maintaining ovarian cancer treatment efficacy in preclinical models.

bioRxiv · Dec 12, 2019 · PreprintCancer Biology