Author

E. d. Stanchina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

A. Barlas· 1 shared A. Nguyen· 1 shared E. Chan· 1 shared E. Weinberg· 1 shared H. Goodarzi· 1 shared H. Li· 1 shared J. A. Boyer· 1 shared J. M. Loo· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Barlas

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tumorigenesis driven by the BRAF V600E oncoprotein requires secondary mutations that overcome its feedback inhibition of migration and invasion

s. gadal, J. A. Boyer, S. F. Roy, N. A. Outmezguine, M. Sharma, H. Li, N. Fan, E. Chan, Y. Romin, A. Barlas, Q. Chang, P. Pancholi, N. M. Timaul, M. Overholtzer, R. Yaeger, , N. Rosen

This study shows that BRAFV600E mutations inhibit cell migration and invasion through feedback inhibition of RAC1, requiring secondary mutations to overcome this block and enable tumorigenesis.

bioRxiv · Nov 21, 2023 · PreprintCancer Biology

PCK1 and DHODH drive colorectal cancer liver metastatic colonization and nucleotide biosynthesis under hypoxia

N. Yamaguchi, E. Weinberg, A. Nguyen, M. V. Liberti, H. Goodarzi, Y. Y. Janjigian, P. B. Paty, L. B. Saltz, T. P. Kingham, J. M. Loo, E. d. Stanchina, S. F. Tavazoie

This study identifies PCK1 and DHODH as drivers of colorectal cancer liver metastasis under hypoxia by promoting nucleotide biosynthesis.

bioRxiv · Nov 7, 2019Cancer Biology