Author

E. H. Egelman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:cryo-EM· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

F. Wang· 3 shared D. Si· 2 shared M. Krupovic· 2 shared V. Cvirkaite-Krupovic· 2 shared W. Zheng· 2 shared A. Hochbaum· 1 shared A. J. McQuown· 1 shared C. H. Chan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBiophysics

F. Wang

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Author profile →

6 papers

Recent·Most cited

Structural elucidation of how ARF small GTPases induce membrane tubulation for vesicle fission

X. Pang, Y. Zhang, K. Park, Z. Liao, J. Li, J. Xu, M.-T. Hong, G. Yin, T. Zhang, Y. Wang, E. H. Egelman, J. Fan, S.-Y. Park, V. W. Hsu, F. Sun

The paper determines the structure of ARF6 protein lattice on tubulated membranes, revealing its role in vesicle fission and how GAP proteins interact with it.

bioRxiv · Dec 19, 2023Cell Biology

Two dramatically distinct archaeal type IV pili structures formed by the same pilin

J. Liu, G. N. Eastep, V. Cvirkaite-Krupovic, S. T. Rich-New, M. A. B. Kreutzberger, E. H. Egelman, M. Krupovic, F. Wang

The paper determines the atomic structures of two distinct archaeal type IV pili formed by the same pilin under different growth conditions, revealing structural flexibility and conformational diversity.

bioRxiv · Aug 7, 2023 · PreprintMicrobiology

Structure of Geobacter OmcZ filaments suggests extracellular cytochrome polymers evolved independently multiple times

F. Wang, C. H. Chan, V. Suciu, K. Mustafa, D. Si, A. Hochbaum, E. H. Egelman, D. Bond

The paper determines the structure of OmcZ filaments in Geobacter sulfurreducens, showing they have a distinct heme arrangement compared to OmcS and OmcE, suggesting independent evolution of conductive cytochrome polymers.

bioRxiv · Jul 17, 2022Biophysics

DeepTracer ID: De Novo Protein Identification from Cryo-EM Maps

L. Chang, F. Wang, K. Connolly, H. Meng, Z. Su, V. Cvirkaite-Krupovic, M. Krupovic, E. H. Egelman, D. Si

DeepTracer-ID identifies proteins from cryo-EM maps without additional sequence information by combining DeepTracer modeling with AlphaFold2 predictions.

bioRxiv · Jun 3, 2022Biophysics

Allosteric Regulation of Human Plastins

C. Schwebach, E. Kudryashova, R. Agrawal, W. Zheng, E. H. Egelman, D. S. KUDRYASHOV

This study investigates how allosteric regulation between actin-binding domains of plastins modulates actin bundling and cross-linking.

bioRxiv · Dec 1, 2021 · PreprintBiochemistry

The AAA+ ATPase TorsinA polymerizes into hollow tubes with a helical periodicity of 8.5 subunits per turn

E. Demircioglu, W. Zheng, A. J. McQuown, N. Maier, N. Watson, I. M. Cheeseman, V. Denic, E. H. Egelman, T. U. Schwartz

This study characterizes the oligomerization of TorsinA, revealing helical filaments with a 8.5 subunit per turn periodicity and membrane tubulation activity.

bioRxiv · Mar 4, 2019Biochemistry