S.-Y. Park

Agrobacterium-mediated Cuscuta campestris transformation as a tool for understanding plant-plant interactions

This paper develops a stable Agrobacterium-mediated transformation protocol for Cuscuta campestris, enabling transgenic plant generation and insights into molecular trafficking during parasitism.

Structural elucidation of how ARF small GTPases induce membrane tubulation for vesicle fission

The paper determines the structure of ARF6 protein lattice on tubulated membranes, revealing its role in vesicle fission and how GAP proteins interact with it.

A compact, ultrahigh-density headstage with high-fidelity hybrid integration for large-scale deep-brain opto-electrophysiology

This paper introduces a high-channel-count optogenetic system for deep-brain studies, achieving high spatial resolution in recording and stimulation with unprecedented channel density.

Debottlenecking and reformulating feed media for improved CHO cell growth and titer by data-driven and model-guided analyses

The paper uses data-driven and model-guided analyses to optimize feed media for improved CHO cell growth and titer by identifying key amino acids and metabolic bottlenecks.

Genetic and transcriptomic analysis of hyphal constriction based on a novel assay method in the rice blast fungus

The paper introduces an in vitro assay to study hyphal constriction in Magnaporthe oryzae, identifying transcriptional changes and a potential histone modification role in this process.

Dose-response relationship for the resistance of human insulin to degradation by insulin-degrading enzyme

The paper investigates how human insulin resistance to degradation by IDE varies with dose and identifies structural features of the insulin hexamer that influence degradation kinetics without zinc.

Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand binding specificity

The paper reports the cryo-EM structure of human SSTR2 bound to somatostatin, revealing ligand binding specificity and interactions with Gi proteins.

Inhibitory effects of β-caryophyllene on Helicobacter pylori infection in vitro and in vivo

This study demonstrates that β-caryophyllene inhibits H. pylori growth and infection through downregulation of virulence factors and bacterial replication machinery, with therapeutic effects confirmed in vivo.

Single-cell transcriptome profiling reveals neutrophil heterogeneity and orchestrated maturation during homeostasis and bacterial infection

This paper uses single-cell RNA sequencing to characterize neutrophil heterogeneity and maturation during homeostasis and bacterial infection, revealing distinct subsets and their functional transitions.

The first finding of lichen Solorina saccata at an algific talus slope in Korea

This study reports the first lichen ecology investigation at an algific talus slope in Korea, identifying 27 lichen species, including the newly recorded Solorina saccata, and predicts its potential habitats in South Korea.