H. Meng

Establishing a straight-forward I-SceI mediated recombination one plasmid system for efficient genome editing in P. putida KT2440

The paper introduces a one-plasmid genome editing system for P. putida KT2440, enabling rapid and efficient genome modifications in three days.

CEP44 is required for maintaining centriole duplication and spindle integrity

This study identifies CEP44's role in preventing centriole overduplication and maintaining spindle integrity, linking it to breast carcinoma prognosis.

High-level production of nervonic acid in the oleaginous yeast Yarrowia lipolytica by systematic metabolic engineering

This study engineered Yarrowia lipolytica to overproduce nervonic acid through metabolic pathway modifications, achieving high titers and purity.

Engineering precise adenine base editor with infinitesimal rates of bystander mutations and off-target editing

This paper engineers a precise adenine base editor, ABE9, with reduced bystander mutations and off-target effects, enabling efficient and accurate A-to-G editing in mouse and rat embryos.

DeepTracer ID: De Novo Protein Identification from Cryo-EM Maps

DeepTracer-ID identifies proteins from cryo-EM maps without additional sequence information by combining DeepTracer modeling with AlphaFold2 predictions.

Adaptive scans allow 3D-targeted laser-dissection to probe the mechanics of cell sheets

This paper introduces a 3D laser dissection system for studying mechanical properties of cell sheets in embryos, demonstrating its application in Drosophila wing imaginal discs.

Genomic Evidence for the Chinese Mountain Cat as a Wildcat Conspecific (Felis silvestris bieti) and Its Introgression to Domestic Cats

The paper uses genomic data to classify the Chinese mountain cat as a wildcat subspecies and finds no evidence of its role in domestic cat domestication in East Asia.

Sex dependent compensatory mechanisms to preserve blood pressure homeostasis in PGI2 receptor deficient mice

This study investigates sex-dependent compensatory mechanisms in blood pressure regulation in PGI2 receptor deficient mice under hyperlipidemic and high salt conditions.

Seasonal Variability and Shared Molecular Signatures of Inactivated Influenza Vaccination in Young and Older Adults

This study identifies shared and seasonal molecular signatures of influenza vaccination in young and older adults, revealing age-specific gene expression patterns linked to antibody responses.

Whole-tree heartwood inducing technique for Dalbergia odorifera

This paper describes a method to induce heartwood formation in Dalbergia odorifera trees, achieving results that meet pharmacopoeia standards.