Author

F. Furnari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

T. Koga· 2 shared A. Caplin· 1 shared A. D. Parisian· 1 shared A. L. Sarver· 1 shared A. S. Venteichera· 1 shared A. W. C. Pang· 1 shared A. Wu· 1 shared B. Chowdhury· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

T. Koga

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Author profile →

4 papers

Recent·Most cited

Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change

S. R. Dehkordi, I. T.-L. Wong, J. Ni, J. Luebeck, K. Zhu, G. Prasad, L. Krockenberger, G. Xu, B. Chowdhury, U. Rajkumar, A. Caplin, D. Muliaditan, C. Coruh, Q. Jin, K. Turner, , V. Bafna

The paper introduces OM2BFB, an algorithm detecting BFB amplifications using OGMs, showing high precision and recall, and finds BFB events are common in certain cancers but not linked to intratumoral heterogeneity or rapid genome change.

bioRxiv · Dec 12, 2023 · PreprintCancer Biology

PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response

J. Li, M. M. Kaneda, J. Ma, M. Li, K. Patel, T. Koga, A. L. Sarver, F. Furnari, B. Xu, S. Dhawan, J. Ning, H. Zhu, A. Wu, G. You, T. Jiang, , C. C. Chen

The paper identifies PI3Kγ as a driver of microglia/macrophage accumulation in glioblastoma, showing its inhibition enhances temozolomide response in preclinical models.

Proceedings of the National Academy of Sciences · Apr 12, 2021Peer-reviewedCancer Biology

Dynamic multi-OMICs of glioblastoma reveal sensitivity to neddylation inhibition dependent on nuclear PTEN and DNA replication pathways

S. R. Ferdosi, B. Taylor, M. Lee, S. Peng, N. Tang, R. Bybee, G. Reid, L. Hartmen, K. Garcia-Mansfield, R. Sharma, P. Pirrotte, F. Furnari, H. D. Dhruv, M. E. Berens

The paper investigates the dynamic multi-OMICs of glioblastoma and identifies sensitivity to neddylation inhibition, though the manuscript was withdrawn due to un reproducible findings.

bioRxiv · Jul 21, 2020 · PreprintCancer Biology

SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability

A. D. Parisian, T. Koga, S. Miki, P. D. Johann, M. Kool, J. R. Crawford, F. Furnari

This study shows SMARCB1 loss affects neuronal differentiation and cell stability differently based on the differentiation state, contributing to ATRT tumorigenesis.

bioRxiv · May 4, 2020Cancer Biology