F. Q. Cunha

Ultrasound inhibits SARS-CoV-2 infectivity in vitro

This study shows ultrasound can reduce SARS-CoV-2 infectivity in vitro without causing heat or cavitation.

Targeting Neutrophils Extracellular Traps (NETs) reduces multiple organ injury in a COVID-19 mouse model

This study shows that DNase I treatment reduces NETs and organ injury in a COVID-19 mouse model.

Sensory neuron-associated macrophages proliferate in the sensory ganglia after peripheral nerve injury in a CX3CR1 signaling dependent manner

This study shows that sensory neuron-associated macrophages proliferate in the sensory ganglia after nerve injury, driven by CX3CR1 signaling, and contribute to inflammation.

Neuraminidase inhibitors rewire neutrophil function in vivo in murine sepsis and ex vivo in COVID-19

This paper shows neuraminidase inhibitors reduce neutrophil overactivation in sepsis and COVID-19 by inhibiting sialic acid release and ROS production.

Zebrafish studies on the vaccine candidate to COVID-19, the Spike protein: Production of antibody and adverse reaction

This study uses zebrafish to test a COVID-19 vaccine candidate, showing antibody production and adverse reactions similar to human severe cases.

Infection of human lymphomononuclear cells by SARS-CoV-2

This study investigates SARS-CoV-2 infection of human lymphomononuclear cells in vitro and in vivo, finding that monocytes, B cells, and T cells are susceptible to infection and viral replication.

Inducible nitric oxide synthase (NOS2) knockout mice as a model of trichotillomania

This study shows that NOS2 knockout mice exhibit increased barbering behavior and repetitive movements, linked to altered NMDA receptor levels and neuronal morphology, suggesting a role for NOS2 in striatal motor regulation.