Author

J. van Schooten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:non-human primate· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

A. B. Ward· 3 shared R. W. Sanders· 3 shared B. Haagmans· 2 shared G. Kerster· 2 shared G. Ozorowski· 2 shared I. A. Wilson· 2 shared I. Bontjer· 2 shared J. L. Torres· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

A. B. Ward

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques.

A. N. Nelson, X. Shen, S. Venkatayogi, S. Zhang, G. Ozorowski, M. Dennis, L. M. Sewall, E. Milligan, D. Davis, K. Cross, Y. Chen, J. van Schooten, J. Eudaily, J. Isaac, S. Memon, , S. R. Permar

This study shows that a multi-dose immunization with germline-targeting SOSIP vaccines induces precursor broadly neutralizing antibodies in infant macaques, similar to adult responses.

bioRxiv · Nov 7, 2023 · PreprintImmunology

CD4-binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wildtype animals

H. B. Gristick, H. Hartweger, M. Loewe, J. van Schooten, V. Ramos, T. Y. Oliviera, Y. Nishimura, N. S. Koranda, A. Wall, K.-H. Yao, D. Poston, A. Gazumyan, M. Wiatr, M. Horning, J. R. Keeffe, , P. J. Bjorkman

This study shows that CD4bs immunogens can elicit potent, broad anti-HIV-1 neutralizing antibodies in transgenic and wildtype animals.

bioRxiv · Sep 8, 2022Immunology

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

P. J. M. Brouwer, M. Brinkkemper, P. Maisonnasse, N. Dereuddre-Bosquet, M. Grobben, M. Claireaux, M. de Gast, R. Marlin, V. Chesnais, S. Diry, J. D. Allen, Y. Watanabe, J. M. Griezen, G. Kerster, H. L. Turner, , de Bree

This paper develops a two-component spike nanoparticle vaccine that protects macaques from SARS-CoV-2 infection by inducing strong neutralizing antibodies and reducing viral replication.

bioRxiv · Nov 7, 2020Immunology

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

H. Liu, N. C. Wu, M. Yuan, S. Bangaru, J. L. Torres, T. G. Caniels, J. van Schooten, X. Zhu, C.-C. D. Lee, P. J. M. Brouwer, M. J. van Gils, R. W. Sanders, A. B. Ward, I. A. Wilson

The paper identifies a SARS-CoV-2 antibody that cross-neutralizes SARS-CoV by binding a conserved epitope and relies on avidity for neutralization.

bioRxiv · Aug 2, 2020Microbiology

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

P. Brouwer, T. Caniels, K. van Straten, J. Snitselaar, Y. Aldon, S. Bangaru, J. Torres, N. Okba, M. Claireaux, G. Kerster, A. Bentlage, M. van Haaren, D. Guerra, J. Burger, E. Schermer, , M. van Gils

This study isolates potent neutralizing antibodies from COVID-19 patients that target multiple sites on the SARS-CoV-2 spike protein, offering insights for vaccine design and therapeutic development.

bioRxiv · May 12, 2020Microbiology

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

C. A. Cottrell, J. van Schooten, C. A. Bowman, M. Yuan, D. Oyen, M. Shin, R. Morpurgo, P. van der Woude, M. van Breemen, J. L. Torres, R. Patel, J. Gross, L. M. Sewall, J. Copps, G. Ozorowski, , M. J. van Gils

This study maps antibody responses to HIV-1 envelope trimers in non-human primates, identifying strain-specific and conserved epitopes recognized by vaccine-induced antibodies.

bioRxiv · Feb 5, 2020Immunology