Author

J. Dye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

A. Herbert· 2 shared B. A. Pinsky· 2 shared C. A. Cohen· 2 shared D. Jochmans· 2 shared D. M. Towers· 2 shared G. C. Ippolito· 2 shared J. D. Gollihar· 2 shared L. Ghita· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. Herbert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Visualizing lipid nanoparticle trafficking for mRNA vaccine delivery in non-human primates

M. Buckley, M. Arainga, L. Maiorino, I. S. Pires, B. J. Kim, K. Kaczmarek Michaels, J. Dye, K. Qureshi, Y. Zhang, H. Mak, J. M. Steichen, W. R. Schief, F. Villinger, D. J. Irvine

This study visualizes lipid nanoparticle trafficking in non-human primates using PET imaging, showing distribution to muscle and draining lymph nodes with uptake by antigen-presenting cells.

bioRxiv · Jun 21, 2024Bioengineering

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

M. Karim, M. Mishra, C.-W. Lo, S. Saul, H. B. Cagirici, D. H. Nhu Tran, A. Agrawal, L. Ghita, A. Ojha, M. P. East, K. Anbro Gammeltoft, M. Kumar Sahoo, G. L. Johnson, S. Das, D. Jochmans, , S. Einav

RMC-113 inhibits PIP4K2C and PIKfyve, reversing SARS-CoV-2-induced autophagic flux impairment and showing antiviral effects.

bioRxiv · Apr 15, 2024Microbiology

Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication, inflammation, and lung injury by a drug repurposing screen

S. Saul, M. Karim, P.-T. Huang, L. Ghita, W. Chiu, S. Kumar, N. Bhalla, P. Leyssen, C. A. Cohen, K. E. Huie, C. Tindle, M. Sibai, B. A. Pinsky, S. Das, P. Ghosh, , S. Einav

This study identifies lapatinib, an ErbB inhibitor, as a broad-spectrum antiviral that suppresses SARS-CoV-2 and VEEV replication, inflammation, and lung injury through ErbB-mediated mechanisms.

bioRxiv · May 15, 2021Microbiology

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes in COVID-19 convalescent plasma

W. N. Voss, Y. J. Hou, N. V. Johnson, J. E. Kim, G. Delidakis, A. P. Horton, F. Bartzoka, C. J. Paresi, Y. Tanno, S. A. Abbasi, W. Pickens, K. George, D. R. Boutz, D. M. Towers, J. R. McDaniel, , G. C. Ippolito

The paper identifies prevalent, protective, and convergent IgG antibodies targeting non-RBD epitopes of SARS-CoV-2 spike protein in convalescent plasma.

bioRxiv · Dec 20, 2020Immunology

Relationship between Anti-Spike Protein Antibody Titers and SARS-CoV-2 In Vitro Virus Neutralization in Convalescent Plasma

E. Salazar, S. V. Kuchipudi, P. A. Christensen, T. N. Eagar, X. Yi, P. Zhao, Z. Jin, S. W. Long, R. J. Olsen, J. Chen, B. Castillo, C. Leveque, D. M. Towers, J. Lavinder, J. D. Gollihar, , J. M. Musser

This study finds a strong correlation between anti-RBD and anti-ECD IgG titers and in vitro virus neutralization titers in convalescent plasma, suggesting these titers can serve as surrogates for neutralizing activity.

bioRxiv · Jun 8, 2020Immunology