Author

N. Elvassore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:development & morphogenesis· 3 Assay:organoid / primary culture· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Organism:rat· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

P. De Coppi· 4 shared C. Luni· 3 shared G. G. Giobbe· 3 shared A. F. Pellegata· 2 shared C. Laterza· 2 shared D. Cacchiarelli· 2 shared E. Naldi· 2 shared F. Michielin· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersBioengineering

P. De Coppi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Prenatal VEGF Nano-Delivery Reverses Congenital Diaphragmatic Hernia-Associated Pulmonary Abnormalities

S. Loukogeorgakis, F. Michielin, S. Shibuya, N. Al-Juffali, J. Jimenez, J. Allen-Hyttinen, P. Eastwood, A. Alhendi, J. Davidson, E. Naldi, P. Maghsoudlou, A. Tedeschi, S. Khalaf, A. Khabbush, M. Plate, , P. De Coppi

This paper investigates VEGF supplementation as a treatment for congenital diaphragmatic hernia (CDH)-associated lung abnormalities using an ex vivo model and nanoparticle-based delivery in vivo.

bioRxiv · Feb 20, 2024Bioengineering

Native extracellular matrix promotes human neuromuscular organoid morphogenesis and function.

B. Auletta, L. Rossi, F. Cecchinato, G. Barbato, A. Lauroja, P. Chiolerio, G. Cecconi, E. Maghin, M. Easler, P. Raffa, S. Angiolillo, W. Qin, S. Calabro, C. Villa, O. Gagliano, , A. Urciuolo

This study shows that decellularized skeletal muscle ECM guides hiPSC differentiation into structured neuromuscular organoids with functional neuromuscular junctions and disease-mimicking contractility.

bioRxiv · May 19, 2023 · PreprintCell Biology

Lung viral infection modelling in a bioengineered whole-organ

F. Tommasini, T. Benoist, S. Shibuya, M. N. J. Woodall, E. Naldi, J. C. Orr, G. G. Giobbe, E. F. Maughan, R. E. Hynds, A. Gjinovci, J. C. Hutchinson, O. J. Arthurs, S. M. Janes, N. Elvassore, C. M. Smith, , P. De Coppi

This paper develops a bioreactor-based whole-organ lung model to study viral infections and demonstrates its use for testing antiviral drugs like Remdesivir.

bioRxiv · Feb 1, 2023Bioengineering

Synchronisation of apical constriction and cell cycle progression is a conserved behaviour of pseudostratified neuroepithelia informed by their tissue geometry

I. Ampartzidis, C. Efstathiou, F. Paonessa, E. M. Thompson, T. Wilson, C. McCann, N. Greene, A. Copp, F. J. Livesey, N. Elvassore, G. G. Giobbe, P. De Coppi, E. Maniou, G. L. Galea

This study shows that neuroepithelial cells synchronize apical constriction with cell cycle progression, but the timing of constriction is influenced by tissue geometry in different regions of the neural tube.

bioRxiv · Jun 15, 2022Cell Biology

SARS-CoV-2 infection and replication in human fetal and pediatric gastric organoids

G. G. Giobbe, F. Bonfante, E. Zambaiti, O. Gagliano, B. C. Jones, C. Luni, C. Laterza, S. Perin, H. T. Stuart, M. Pagliari, A. Bortolami, E. Mazzetto, A. Manfredi, C. Colantuono, L. Di Filippo, , P. De Coppi

This paper shows that SARS-CoV-2 can infect and replicate in pediatric gastric organoids but not in fetal ones, suggesting differential susceptibility based on developmental stage.

bioRxiv · Jun 24, 2020Cell Biology