Author

G. R. Medigeshi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Awasthi· 2 shared D. Sok· 2 shared G. Batra· 2 shared J. Bhattacharya· 2 shared J. Singh· 2 shared J. Sutar· 2 shared M. Y. Ansari· 2 shared N. Hingankar· 2 shared

Activity by Year

2021-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. Awasthi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Ancestral SARS-CoV-2 driven antibody repertoire diversity in an unvaccinated individual correlates with expanded neutralization breadth

S. Deshpande, M. Y. Ansari, J. Sutar, P. Das, N. Hingankar, S. Mukherjee, P. Jayal, S. Singh, A. Anantharaj, J. Singh, S. Chattopadhyay, S. Raghavan, M. Gosain, S. Chauhan, S. Shrivas, , J. Bhattacharya

The paper examines antibody diversity in an unvaccinated SARS-CoV-2 infected individual, finding that post-vaccination neutralization breadth against Omicron variants is comparable to vaccinated individuals and breakthrough infections.

bioRxiv · Oct 19, 2022Immunology

A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 delta variant

N. Hingankar, S. Deshpande, P. Das, Z. A. Rizvi, A. Burns, S. Barman, F. Zhao, M. Y. Ansari, S. Mukherjee, J. L. Torres, S. Chattopadhyay, F. Mehdi, J. Sutar, D. K. Rathore, K. Pargai, , J. Bhattacharya

This paper identifies two potent monoclonal antibodies from an Indian donor that neutralize SARS-CoV-2 variants including Delta, showing protection in a mouse model.

bioRxiv · Dec 25, 2021Immunology

A vitamin D-RelB/NF-κB pathway limits Chandipura virus multiplication by rewiring the homeostatic state of autoregulatory type 1 interferon-IRF7 signaling

Y. Ratra, N. Kumar, M. K. Saha, C. Bharadwaj, C. Chongtham, S. S. Bais, G. R. Medigeshi, G. A. Arimbasseri, S. Basak

This study identifies a vitamin D-RelB/NF-κB pathway that limits Chandipura virus multiplication by enhancing type 1 interferon production through IRF7 autoregulation.

bioRxiv · Nov 1, 2021Immunology

Immunophenotyping and transcriptional profiling of human plasmablasts in dengue.

C. Aggarwal, K. Saini, E. S. Reddy, M. Singla, K. Nayak, Y. Chawla, D. Maheshwari, P. Singh, P. Sharma, P. Bhatnagar, S. Kumar, K. Gottimukkala, H. Panda, S. Gunisetty, C. W. Davis, , A. Chandele

This study characterizes plasmablasts in dengue patients from India, showing their transcriptional features, adhesion molecule expression, and differential expansion based on infection severity.

bioRxiv · Apr 9, 2021Immunology

Immunological and cardio-vascular pathologies associated with SARS-CoV-2 infection in golden syrian hamster

Z. A. Rizvi, R. Dalal, S. Sadhu, Y. Kumar, T. Shrivastava, S. K. Gupta, S. Aggarwal, M. R. Tripathy, A. K. Yadav, G. R. Medigeshi, A. K. Pandey, S. Samal, S. Asthana, A. Awasthi

This study shows that SARS-CoV-2 infection in golden Syrian hamsters causes lung and cardiovascular pathologies similar to human COVID-19, suggesting GSH as a model for studying long-term effects.

bioRxiv · Jan 11, 2021Microbiology