A. K. Pandey

Nitrogen Management on Improving Resilience of Flood-Tolerant (Sub1) Rice Varieties in Flood-Prone Rainfed Lowlands

This study investigates the effect of nitrogen management on the survival and productivity of flood-tolerant rice varieties, finding that a specific nitrogen application strategy improves submergence tolerance and yield.

Identifying the genetic and epigenetic basis for asymmetric bZIP expression in temperature-stressed bread wheat

This study investigates the genetic and epigenetic factors underlying asymmetric bZIP expression in bread wheat under temperature stress.

VapC12 ribonuclease toxin modulates host immune response during Mycobacterium tuberculosis infection

This study shows that the VapC12 toxin in Mycobacterium tuberculosis modulates host immune responses, promoting pathogen survival by altering T-cell and neutrophil responses.

Jasmonates regulate auxin-mediated root growth inhibition in response to rhizospheric pH in Arabidopsis

The paper identifies a mechanistic framework for rhizospheric pH-mediated root growth inhibition in Arabidopsis through the interaction between auxin and jasmonates.

Hypothetical gene Rv0495c regulates redox homeostasis in Mycobacterium tuberculosis

This study identifies Rv0495c as a regulator of redox homeostasis in Mtb, showing that its absence increases ROS and susceptibility to stress, yet enhances pathogenicity in host models.

Establishing Ac/Ds Starter Lines for Large-Scale Transposon-Tagged Mutagenesis in Tomato

The paper develops two tomato starter lines with maize transposon elements and transposase to enable large-scale transposon mutagenesis for gene functional validation.

Chemical inhibition of histidine biosynthesis curtails M. tuberculosis infection

This study designs triazole inhibitors targeting M. tuberculosis's histidine biosynthesis pathway, showing efficacy against drug-resistant strains and reducing bacterial burden in infected mice.

Deferoxamine as adjunct therapeutics for tuberculosis

This study shows Deferoxamine (DFO) has antimycobacterial properties and can reduce Mtb burden when used as an adjunct to standard tuberculosis treatments.

An efficient hairy root system for genome editing of a β-ODAP pathway gene in Lathyrus sativus

This paper develops a hairy root system for genome editing of the LsOCS gene in Lathyrus sativus to study its role in β-ODAP production and oxalate accumulation.

System analysis of differentially expressed miRNAs in hexaploid wheat display tissue-specific regulatory role during Fe deficiency response

The paper identifies Fe deficiency-responsive miRNAs in hexaploid wheat and shows their tissue-specific regulation and potential targets involved in Fe homeostasis.

A comparative study of low-pH tolerance and chitinase activity between toxigenic and non-toxigenic strains of Vibrio cholerae

This study compares low-pH tolerance and chitinase activity between toxigenic and non-toxigenic Vibrio cholerae strains, finding that the non-toxigenic strain exhibits greater growth and chitinase activity under acidic conditions.

Rab7 dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

This study shows Rab7 regulates CLCA1 in goblet cells, affecting mucus composition and gut microbiota, leading to increased susceptibility to colitis.

Transcriptome and biochemical analysis pinpoint multi-layered molecular processes associated with iron deficiency tolerance in hexaploid wheat

This study identifies molecular and biochemical mechanisms underlying Fe deficiency tolerance in hexaploid wheat by comparing tolerant and susceptible cultivars.

Understanding water conservation vs. profligation traits in vegetable legumes through a physio-transcriptomic-functional approach

This study compares water use strategies in soybean and cowpea under drought using phenomic and transcriptomic analyses, identifying gene networks and regulatory mechanisms underlying their contrasting responses.

Asymmetric expression of homoeologous genes in wheat roots modulates the early phase of iron-deficiency signalling

This study examines the transcriptional response of wheat roots to iron deficiency at early stages, identifying dynamic gene expression and homoeologous gene expression patterns.

Elongated Hypocotyl 5 (HY5) regulates BRUTUS (BTS) to maintain Iron homeostasis in Arabidopsis thaliana.

This study shows HY5 regulates Fe deficiency responses in Arabidopsis by modulating BTS and Fe uptake genes.

Proinflammatory innate cytokines and metabolomic signatures shape the T cell response in active COVID-19

The paper examines how proinflammatory cytokines and metabolomic signatures influence T cell responses in active COVID-19 patients, showing preserved T cell responses against variants despite reduced antibody responses.

Hydrothermal Synthesis of Clove Bud-Derived Multifunctional Carbon Dots Passivated with PVP- Antioxidant, Catalysis, and Bioimaging Applications

This study synthesizes PVP-passivated clove bud-derived carbon dots with antioxidant, catalytic, and bioimaging properties using a hydrothermal method.

Wheat inositol pyrophosphate kinase TaVIH2-3B modulates cell-wall composition for drought tolerance in Arabidopsis

This study identifies TaVIH2-3B, a wheat PPIP5K homolog, which enhances drought tolerance in Arabidopsis by modulating cell-wall composition through increased polysaccharide accumulation.

Immunological and cardio-vascular pathologies associated with SARS-CoV-2 infection in golden syrian hamster

This study shows that SARS-CoV-2 infection in golden Syrian hamsters causes lung and cardiovascular pathologies similar to human COVID-19, suggesting GSH as a model for studying long-term effects.

Genetic screen to saturate guard cell signaling network reveals a role of GDP-L-fucose metabolism in stomatal closure

The paper identifies a novel role for GDP-L-fucose metabolism in stomatal closure through a genetic screen, revealing defects in fucose-related processes affect guard cell function.

Physiological and molecular responses to combinatorial iron and phosphate deficiencies in hexaploid wheat seedlings

This study examines how hexaploid wheat responds to iron and phosphate deficiencies, finding that combined deficiencies rescue root growth inhibition and trigger specific gene and metabolite changes.

An Inherent Structural Difference Between Serine and Threonine Phosphorylation: Phosphothreonine Prefers an Ordered, Compact, Cyclic Conformation

This study identifies a structural difference between serine and threonine phosphorylation, showing phosphothreonine adopts a compact, cyclic conformation with specific torsions.

Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag

The paper identifies four unique inserts in the 2019-nCoV spike protein that show similarity to HIV-1 gp120 and Gag, suggesting potential evolutionary links and implications for viral function and diagnosis.

Gene expression pattern of vacuolar-iron transporter-like (VTL) genes in hexaploid wheat during metal stress

This study characterizes VTL genes in hexaploid wheat, showing their expression patterns under metal stress and their potential role in metal homeostasis.

Host cholesterol dependent activation of VapC12 toxin enriches persister population during Mycobacterium tuberculosis infection

This study identifies cholesterol-dependent activation of the VapC12 toxin in Mycobacterium tuberculosis as a mechanism that increases persister formation during infection.

Integrative analysis of hexaploid wheat roots identifies signature components during iron starvation

This study identifies gene and metabolic signatures in hexaploid wheat roots under iron starvation, revealing key transporters and metabolites involved in Fe acquisition and response.

Overlapping transcriptional expression response of wheat zinc-induced facilitator-like transporters emphasize important role during Fe and Zn stress

The paper identifies and analyzes wheat ZIFL transporters, showing their differential expression under Fe and Zn stress and heavy metal exposure.

MutS-Homolog2 Silencing Generates Tetraploid Meiocytes In Tomato (Solanum lycopersicum)

This study shows that silencing MSH2 in tomato leads to tetraploid meiocytes and abnormal pollen formation due to disrupted meiosis and ploidy stability.