G. Zhao

This paper develops membrane nanoparticles from ACE2-rich cells that effectively block SARS-CoV-2 infection by trapping the viral S1 protein and inhibiting its interaction with host cells.

This study shows that a recombinant SARS-CoV-2 S1-Fc fusion protein induces strong neutralizing antibodies in nonhuman primates and can be produced at scale for vaccine development.

This study identifies CD209L/L-SIGN and CD209/DC-SIGN as alternative receptors for SARS-CoV-2, capable of mediating virus entry into human cells, particularly in tissues with low ACE2 expression.

The paper identifies FZD7 as a marker of platinum-tolerant ovarian cancer cells that are susceptible to ferroptosis via the FZD7-β-catenin-Tp63-GPX4 pathway.

This paper develops a novel mouse model for SARS-CoV-2 infection and evaluates the protective efficacy of an RBD-based subunit vaccine.

This study introduces Aspergillus fumigatus α-1,2-mannosidase MsdS into Trichoderma reesei, altering N-glycan processing and improving lignocellulose degradation while causing abnormal polarity and secretion phenotypes.

The paper investigates how lectin-like intestinal defensin HD5 inhibits 2019-nCoV Spike protein binding to ACE2, showing a high-affinity interaction and protective effect in vitro.

This study shows SPOP promotes ubiquitination and degradation of MyD88, suppressing innate immune responses and reducing susceptibility to Salmonella typhimurium infection.

This study shows that HMGB1 release in response to mechanical overloading causes inflammation and tendinopathy in mice, which can be blocked by glycyrrhizin.

The paper shows Ctf4 organizes sister replisomes and Pol alpha into a replication factory by dimerizing CMG helicase and binding one Pol-primase.

This study determines the structure of an E. coli transcription activation complex and shows that Crl stabilizes σS to activate transcription without DNA contact.

This study identifies the gene cluster and key enzymes involved in pyrazomycin biosynthesis in Streptomyces candidus, revealing the role of PyrR as a transcriptional activator and PyrN as a nitrogen-nitrogen bond-forming enzyme.

This study analyzes the pan-genome of Staphylococcus epidermidis to identify genomic factors associated with its adaptation to diverse niches and pathogenicity.

This study analyzes soil nutrient variability and its impact on winter wheat growth stages in northern China under traditional tillage, finding nutrient content and growth correlations change over time.

This paper identifies BceR as a key regulator in Group B Streptococcus virulence, antimicrobial resistance, and stress response through functional analysis of a non-invasive strain.

This study identifies PafE as an ATP-independent proteasome activator in M. tuberculosis, revealing its mechanism of substrate capture and gate activation through structural and functional analyses.

This study tests eDNA detection for invasive crayfish in rice terraces, finding it more sensitive than trapping and suggesting repeated sampling for reliable monitoring.