The p53-p21-Cyclin D2 regulatory axis drives metabolic reprogramming and a distinct senescent macrophage senotype during aging and MASLD.
Grasiela Torres, Ivan Alexander Salladay-Perez, Christina Y. Deng, Itzetl Avila, Yennifer Delgado, Gregory Tong, Jesús Muñoz‐Estrada, Lizeth Estrada, Anika Dhingra, Wesley Robert Armstrong, Aishini Singh, Isabella Cooper, Eduardo Enriquez, Prashant Kaushal, Jocelyn Ni, , Anthony J. Covarrubias
bioRxiv · Sep 28, 2026 · PreprintImmunology