Author

Guojing Zhu

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Audrey C. A. CleureniD· 3 shared David R. Siemieniak· 3 shared Randal Joseph WestrickiD· 3 shared Amy E. SiebertiD· 2 shared David GinsburgiD· 2 shared Emilee N. KotnikiD· 2 shared Kärt TombergiD· 2 shared Marisa A BrakeiD· 2 shared

Activity by Year

2017-2026 · peak 1/yr

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10 top collaborators · 41 mutual co-author links

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3 shared papersGenetics

Audrey C. A. CleurenORCID

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3 papers

Recent·Most cited

A Sensitized ENU Mutagenesis Screen for Thrombosis Modifiers Identifies Suppressor Variants in Non-mutagenized Parental Generations Due to Antithrombotic Selective Pressures

Marisa A Brake, Audrey C. A. Cleuren, Sydney J. Torres, Martijn A. van der Ent, Guojing Zhu, Justin R. Kulchycki, Tyler M. Parsons, Caitlin D. Schneider, Adrianna M. Jurek, Kailey H MacFadyen, Amy E. Siebert, David R. Siemieniak, Andrew E. Timms, David R. Beier, Randal Joseph Westrick

The paper identifies four spontaneous mutations that confer survival in a thrombosis model by reducing platelet aggregation and altering gene expression.

bioRxiv · Jan 25, 2026 · PreprintGenetics

Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse

Kärt Tomberg, Randal Joseph Westrick, Emilee N. Kotnik, David R. Siemieniak, Guojing Zhu, Thomas L. Saunders, Audrey C. A. Cleuren, David Ginsburg

The paper identifies a de novo mutation in Plcb4 that suppresses thrombosis in mice with Factor V Leiden and tissue factor pathway inhibitor mutations.

PLoS Genetics · Sep 6, 2018Peer-reviewedGenetics

A sensitized mutagenesis screen in Factor V Leiden mice identifies novel thrombosis suppressor loci

Randal Joseph Westrick, Kärt Tomberg, Amy E. Siebert, Guojing Zhu, Mary E. Winn, Sarah L. Dobies, Sara L. Manning, Marisa A Brake, Audrey C. A. Cleuren, Linzi M Hobbs, Lena M. Mishack, Alexander J. Johnston, Emilee N. Kotnik, David R. Siemieniak, Jishu Xu, , David Ginsburg

The paper identifies novel thrombosis suppressor loci using a sensitized mutagenesis screen in Factor V Leiden mice, finding F8 and the Tfpi/F3 axis, as well as Actr2, play key roles in thrombosis regulation.

Proceedings of the National Academy of Sciences · Aug 21, 2017Peer-reviewedGenetics