Author

T. P. L. Bijl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

R. W. Sanders· 3 shared A. Antanasijevic· 2 shared A. Ward· 2 shared D. Guerra· 2 shared G. Ozorowski· 2 shared J. A. Burger· 2 shared J. L. Torres· 2 shared K. Sliepen· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersImmunology

R. W. Sanders

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Broad SARS-CoV-2 Neutralization by Monoclonal and Bispecific Antibodies Derived from a Gamma-infected Individual

D. Guerra, T. Beaumont, L. Radic, G. Kerster, K. van der Straten, M. Yuan, J. L. Torres, W.-H. Lee, H. Liu, M. Poniman, I. Bontjer, J. A. Burger, M. Claireaux, T. G. Caniels, J. L. Snitselaar, , M. J. van Gils

This study identifies broadly neutralizing monoclonal and bispecific antibodies from a Gamma variant-infected individual that effectively neutralize multiple SARS-CoV-2 variants.

iScience · Oct 1, 2023Peer-reviewedImmunology

Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19

C. E. Geyer, H.-J. Chen, A. P. Bye, X. D. Manz, D. Guerra, T. G. Caniels, T. P. L. Bijl, G. R. Griffith, W. Hoepel, S. W. de Taeye, J. Veth, A. P. J. Vlaar, Amsterdam UMC COVID-19 Biobank, G. Vidarsson, H. J. Bogaard, , J. den Dunnen

The paper identifies SYK and PI3K inhibitors, particularly entospletinib, as effective in counteracting anti-spike IgG-induced hyperinflammation in severe COVID-19.

bioRxiv · Dec 20, 2022Immunology

Lassa virus glycoprotein nanoparticles elicit a neutralizing antibody that defines a new site of vulnerability

P. J. M. Brouwer, A. Antanasijevic, A. J. Ronk, H. Mulller-Krauter, Y. Watanabe, M. Claireaux, N. M. Lloyd, T. P. L. Bijl, H. R. Perrett, T. H. Steijaert, J. A. Burger, M. M. van Haaren, K. Sliepen, M. van Gils, M. Crispin, , R. W. Sanders

This study develops Lassa virus glycoprotein nanoparticles that stabilize GPC trimers and elicit neutralizing antibodies targeting a new vulnerability site.

bioRxiv · Mar 28, 2022 · PreprintImmunology

Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles

P. J. M. Brouwer, A. Antanasijevic, M. de Gast, J. D. Allen, J. D. Allen, T. P. L. Bijl, A. Yasmeen, R. Ravichandran, J. Burger, G. Ozorowski, J. L. Torres, C. LaBranche, D. Montefiori, R. P. Ringe, M. van Gils, , R. W. Sanders

This study shows that displaying HIV-1 Env trimers on two-component protein nanoparticles enhances autologous Tier-2 neutralizing antibody titers in rabbits.

bioRxiv · Nov 30, 2020Microbiology