Author

S. Ozaki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

D. Yamashita· 3 shared I. Nakano· 3 shared T. Kondo· 3 shared T. Kunieda· 3 shared D. Crossman· 2 shared D.-H. Nam· 2 shared H. J. Cho· 2 shared H. Kornblum· 2 shared

Activity by Year

2020-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

D. Yamashita

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Digital control of c-di-GMP in E. coli balances population-wide developmental transitions and phage sensitivity

A. Reinders, B. Sellner, F. Fadel, M. van Berkum, A. Kaczmarczyk, S. Ozaki, J. Rueher, P. Manfredi, M. Sangermani, A. Harms, C. Perez, T. Schirmer, U. Jenal

This study shows E. coli uses a digital switch to convert c-di-GMP dynamics into binary states, enabling population-level developmental transitions and phage resistance.

bioRxiv · Oct 1, 2021 · PreprintMicrobiology

Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge

D. Yamashita, D. Botta, H. J. Cho, X. Guo, S. Ozaki, V. L. Flanary, I. Sirota, M. Gao, S. Yamaguchi, M. A. Nakano, F. Zhou, H. Zhou, T. Kondo, T. Kunieda, D. Crossman, , I. Nakano

This study identifies clonal subpopulations in glioblastoma core and edge lesions and shows that NAD+ depletion via CD38 inhibition reduces tumor edge formation.

bioRxiv · Nov 26, 2020 · PreprintCancer Biology

Brain aging-dependent glioma traits reversible by NAD+/BDNF-mediated neuronal reactivation

D. Yamashita, V. L. Flanary, R. B. Munk, K. Sonomura, S. Ozaki, R. Kawaguchi, S. Suehiro, S. Bastola, M. S. Pavlyukov, S. Yamaguchi, M. A. Nakano, T. Kunieda, D. Hambardzumyan, T. Kondo, H. Kornblum, , I. Nakano

This study shows that aging reduces neuronal signaling in gliomas, but NAD+ and BDNF can reverse these effects, improving outcomes in older mice.

bioRxiv · Oct 10, 2020 · PreprintCancer Biology

Tumor Edge-to-Core Transition Promotes Malignancy in Primary-to-Recurrent Glioblastoma Progression in a PLAGL1/CD109-mediated mechanism

C. Li, H. J. Cho, D. Yamashita, M. Abdelrashid, Q. Chen, S. Bastola, G. Chagoya, G. A. Elsayed, S. Komarova, S. Ozaki, Y. Ohtsuka, T. Kunieda, H. I Kornblum, T. Kondo, D.-H. Nam, I. Nakano

The paper identifies a CD133down/CD109up signature associated with poor prognosis in glioblastoma recurrence and shows PLAGL1 mediates tumor progression through CD109 regulation.

bioRxiv · Sep 14, 2020Cancer Biology

Epstein-Barr virus tegument protein BGLF2 in exosomes released from virus-producer cells assists de novo infection

Y. Sato, M. Yaguchi, Y. Okuno, H. Ishimaru, S. Ozaki, T. Suzuki, T. Inagaki, M. Umeda, T. Watanabe, M. Fujimuro, T. Murata, H. Kimura

This study identifies BGLF2, an EBV tegument protein, as being encapsulated in exosomes that enhance viral infection by boosting gene expression and suppressing innate immunity.

bioRxiv · Jun 22, 2020 · PreprintMicrobiology