S. Yamaguchi

Biosynthesis of gibberellin-related compounds modulates far-red light responses in the liverwort Marchantia polymorpha

This study shows that GA-related compounds in liverworts modulate far-red light responses, revealing evolutionary conservation and functional divergence in GA biosynthesis.

Chemoenzymatic fluorescence labeling of intercellularly contacting cells using lipidated sortase A

This study develops a method to selectively label intercellularly contacting cells using chemoenzymatic approaches, validated by microscopy and flow cytometry.

An ancestral function of strigolactones as symbiotic rhizosphere signals

This study identifies BSB, an ancestral strigolactone in bryophytes, which functions as a rhizosphere signal for AM symbiosis and was later co-opted as a plant hormone.

Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge

This study identifies clonal subpopulations in glioblastoma core and edge lesions and shows that NAD+ depletion via CD38 inhibition reduces tumor edge formation.

Brain aging-dependent glioma traits reversible by NAD+/BDNF-mediated neuronal reactivation

This study shows that aging reduces neuronal signaling in gliomas, but NAD+ and BDNF can reverse these effects, improving outcomes in older mice.

Thermostable mutants of glycoside hydrolase family 6 cellobiohydrolase from the basidiomycete Phanerochaete chrysosporium

This study identifies thermostable mutants of PcCel6A, a glycoside hydrolase family 6 cellobiohydrolase, by analyzing the impact of cysteine residues on thermal stability.

Chemical identification of 18-hydroxycarlactonoic acid as an LjMAX1 product and conversion of 18-hydroxylcarlactonoates to canonical and non-canonical strigolactones in Lotus japonicus

This study identifies LjMAX1 as the key enzyme in Lotus japonicus strigolactone biosynthesis, showing it converts carlactone to 18-hydroxycarlactonoic acid, a precursor for both canonical and non-canonical strigolactones.

Growth- and stress-related defects associated to wall hypoacetylation are strigolactone-dependent

The paper shows that strigolactone biosynthesis compensates for wall hypoacetylation defects in Arabidopsis, suggesting SL pathway activation is a response to wall structural changes.