Author

I. Bagdonaite

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Y.-H. Chen· 3 shared C. J. Mycroft-West· 2 shared H. H. Wandall· 2 shared J. E. Turnbull· 2 shared M. A. Lima· 2 shared M. A. Skidmore· 2 shared S. E. Guimond· 2 shared T. Bergstrom· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersMicrobiology

Y.-H. Chen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Glycoengineered keratinocyte library reveals essential functions of specific glycans for all stages of HSV-1 infection

I. Bagdonaite, I. N. Marinova, A. M. Rudjord-Levann, E. M. Pallesen, S. King-Smith, T. B. Roemer, Y.-H. Chen, S. Olofsson, R. Norden, T. Bergstrom, S. Dabelsteen, H. H. Wandall

The paper uses a glycoengineered keratinocyte library to identify specific glycans essential for different stages of HSV-1 infection.

bioRxiv · Oct 23, 2022Microbiology

Isoform-specific O-glycosylation dictates Ebola virus infectivity

I. Bagdonaite, S. Abdurahman, M. Mirandola, M. Frank, Y. Narimatsu, S. Y. Vakhrushev, C. Salata, A. Mirazimi, H. H. Wandall

This study shows that specific O-glycosylation of Ebola virus glycoprotein affects viral infectivity and identifies key host enzymes involved in this process.

bioRxiv · Apr 25, 2022 · PreprintMicrobiology

The hyperlipidaemic drug fenofibrate significantly reduces infection by SARS-CoV-2 in cell culture models

S. P. Davies, C. J. Mycroft-West, I. Pagani, H. J. Hill, Y.-H. Chen, R. T. Karlsson, I. Bagdonaite, S. E. Guimond, Z. Stamataki, M. A. Lima, J. E. Turnbull, Z. Yang, E. E. Vicenzi, M. A. Skidmore, F. Khanim, A. Richardson

This study shows fenofibrate and its metabolite fenofibric acid reduce SARS-CoV-2 infection in cell culture by up to 70% at clinically achievable concentrations.

bioRxiv · Jan 10, 2021Pharmacology & Toxicology

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

S. E. Guimond, C. J. Mycroft-West, N. S. Gandhi, J. A. Tree, T. T. Le, C. M. Spalluto, M. V. Humbert, K. R. Buttigieg, N. Coombes, M. J. Elmore, K. Nystrom, J. Said, Y. X. Setoh, A. Amarilla, N. Modhiran, , J. E. Turnbull

This paper shows that pixatimod inhibits SARS-CoV-2 by disrupting the Spike-ACE2 interaction, demonstrating its potential as an anti-COVID-19 therapeutic.

bioRxiv · Jun 24, 2020Microbiology