Author

Haitian Zhou

University of California, Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:wet-lab / biochemical assay· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea NansiD· 1 shared Angie Lackner· 1 shared Anna Wu· 1 shared Clancy W. MullaniD· 1 shared Dan Jane‐witiD· 1 shared Doryen BubeckiD· 1 shared Dylan P. NooneiD· 1 shared Feixuan Chi· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Andrea NansORCID

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2 papers

Recent·Most cited

Internalized Components of Membrane Attack Complexes Disrupt Proteostasis and Acquire Alarmin-Like Properties

宋贵玉, Zihan Ma, Matthew Fan, Liying He, Yulong Lan, Weihao Li, Zhengtao Jiang, Quan Jiang, Dylan P. Noone, Andrea Nans, Kamal L. Nahas, Mahsa Nouri Barkestani, Shaoxun Wang, Qianxun Wang, Pengwei Ren, , Dan Jane‐wit

This study shows that C9, a component of membrane attack complexes, forms non-cytolytic intracellular aggregates that promote inflammation and EC activation through aggrephagy and NF-κB activation.

Nature Communications · Jul 17, 2026Peer-reviewedBiochemistry

NLRP10 Cleaves Oxidized DNA inhibited by OGG1 inhibitors: A Newly Identified Role in DNA Damage Processing and Senescence Regulation.

Julia Elise Cabral, Sophia Lin, Haitian Zhou, Anna Wu, Angie Lackner, Minh Anh Pham, Feixuan Chi, Reginald McNulty

This study identifies NLRP10's role in cleaving oxidized DNA and its impact on senescence and inflammasome activation through interactions with NLRP3.

bioRxiv · Mar 7, 2025 · PreprintImmunology