Author

Hani Hosseini Far

Hudson Institute of Medical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra L. McAllaniD· 2 shared Paul J. HertzogiD· 2 shared Antony Y. MatthewsiD· 1 shared Arwaf S. AlharbiiD· 1 shared Ben CorryiD· 1 shared Cameron R. StewartiD· 1 shared Carola G. VinuesaiD· 1 shared Carrie BerneckyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Alexandra L. McAllanORCID

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2 papers

Recent·Most cited

2'-O-Methyl-guanosine 3-base RNA fragments mediate essential natural TLR7/8 antagonism

Arwaf S. Alharbi, Sunil Sapkota, Zhikuan Zhang, Ruitao Jin, Erandi Rupasinghe, W. Samantha N. Jayasekara, Dingyi Yu, Mary Speir, Lorna E. Wilkinson‐White, Liza Cubeddu, Julia I. Ellyard, Refaya Rezwan, Daniel S. Wenholz, Alexandra L. McAllan, Rui Gao, , Michael Paul Gantier

The paper identifies 2'-O-methyl-guanosine RNA fragments as natural antagonists of TLR7/8, preventing auto-immunity by inhibiting TLR signaling.

Nature Immunology · Feb 10, 2026Peer-reviewedImmunology

Annexin A2 mediates RIG-I-like receptor responses to viral infection

Georgie Wray‐McCann, David Michalík, Alexandra L. McAllan, Linden J. Gearing, Roxanne Hsiang-Chi Liou, Nicole K. Campbell, Sarah Straub, Hani Hosseini Far, Antony Y. Matthews, Michelle D. Tate, Sophia Davidson, Roman Fisher, Carrie Bernecky, Jan Rehwinkel, Paul J. Hertzog, Natália G. Sampaio

This study identifies Annexin A2 as a critical mediator of RIG-I-like receptor responses to viral infection by promoting MDA5 oligomerization and enhancing interferon production.

bioRxiv · Oct 28, 2025 · PreprintImmunology