Author

Christopher C. Glembotski

San Diego State UniversityORCID 0000-0002-1380-5073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Erik A. BlackwoodiD· 2 shared Alina S. BilaliD· 1 shared Ankit TripathiiD· 1 shared Annika Decker· 1 shared Bin LiuiD· 1 shared Christoph P. HofmanniD· 1 shared Clara SandmanniD· 1 shared Dan YiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Erik A. BlackwoodORCID

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Author profile →

3 papers

Recent·Most cited

Single-cell and Spatial Transcriptomics Identified Fatty Acid-binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension

Bin Liu, Dan Yi, Shuai Li, Karina Ramirez, Xiaomei Xia, Yanhong Cao, Hanqiu Zhao, Ankit Tripathi, Shenfeng Qiu, Mrinalini Kala, Ruslan Rafikov, Haiwei Gu, Vinicio de Jesús Pérez, Sarah-Eve S Lemay, Christopher C. Glembotski, , Zhiyu Dai

The paper identifies FABP4/5 as key regulators of endothelial glycolysis and arterial programming in pulmonary hypertension using single-cell and spatial transcriptomics.

Arteriosclerosis Thrombosis and Vascular Biology · May 22, 2025Peer-reviewedMolecular Biology

Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimers disease hallmarks

Nikhil Dave, Jessica M. Judd, Annika Decker, Wendy Winslow, Patrick Sarette, Oscar Villarreal Espinosa, Savannah Tallino, Samantha K. Bartholomew, Alina S. Bilal, Jessica Sandler, Ian McDonough, Joanna K. Winstone, Erik A. Blackwood, Christopher C. Glembotski, Timothy L. Karr, Ramón Velázquez

This study shows that dietary choline deficiency in AD model mice leads to organ pathology and worsens Alzheimer's disease hallmarks.

Aging Cell · Jan 15, 2023Peer-reviewedNeuroscience

Age-related decline of the unfolded protein response in the heart promotes protein misfolding and cardiac pathology

Christoph P. Hofmann, Erik A. Blackwood, Tobias Jakobi, Clara Sandmann, Julia Groß, Nicole Herzog, Randal J. Kaufman, Hugo Albert Katus, Mirko Völkers, Christopher C. Glembotski, Shirin Doroudgar

This study shows that the unfolded protein response declines with age in the heart, leading to protein misfolding and cardiac dysfunction.

bioRxiv · Jun 16, 2021 · PreprintMolecular Biology