Author

M. Z. Krauss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:differential expression· 1

Frequent Co-Authors

M. R. Hepworth· 4 shared R. K. Grencis· 2 shared A. Charton· 1 shared A. Villegas-Mendez· 1 shared A. Waisman· 1 shared C. Godinho-Silva· 1 shared C. Purse· 1 shared D. Bechtold· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersImmunology

M. R. Hepworth

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4 papers

Recent·Most cited

Distinct eosinophil subsets are modulated by agonists of the commensal-metabolite and vitamin B3 receptor GPR109A during allergic-type inflammation

R. Azzoni, K. J. Filbey, R. H. Daw, M. Z. Krauss, M. R. Hepworth, J. E. Konkel, E. M. Hessel, Y. Kannan, J. R. Grainger

The paper identifies GPR109A as a regulator of glycolytic Siglec-Fhi eosinophils during allergic inflammation, showing that GPR109A ligands reduce their frequency and activation.

bioRxiv · Aug 4, 2022 · PreprintImmunology

Rhythmicity of Intestinal IgA Responses Confers Oscillatory Commensal Microbiota Mutualism

H. A. Penny, R. G. Domingues, M. Z. Krauss, F. Melo-Gonzalez, S. Dickson, J. Parkinson, M. Hurry, C. Purse, E. Jegham, C. Godinho-Silva, M. Rendas, H. Veiga-Fernandes, D. Bechtold, R. K. Grencis, K.-M. Toellner, , M. R. Hepworth

This study shows diurnal rhythms in intestinal IgA regulate oscillations in commensal microbiota abundance, promoting mutualism.

bioRxiv · Oct 11, 2021Immunology

Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection

D. Hudrisier, D. Corral, A. Charton, M. Z. Krauss, E. Blanquart, F. Levillain, E. Lefrancais, T. Sneperger, J.-P. Girard, G. Eberl, Y. Poquet, J.-C. Guery, R. J. Arguello, M. R. Hepworth, O. Neyrolles

This study shows that Mycobacterium tuberculosis infection drives immature lung ILC2 to differentiate into ILC1-like cells through type 1 cytokines and a glycolytic program controlled by HIF1.

bioRxiv · Jan 19, 2021Immunology

Large Neutral Amino acid uptake and mTOR activation within CD4+ T cells coordinate Type 2 immunity and host resistance to Trichuris muris

M. Z. Krauss, K. S. Hayes, A. Villegas-Mendez, M. R. Hepworth, L. V. Sinclair, K. N. Couper, R. K. Grencis

This study shows that SLC7A5-mediated mTOR activation in CD4+ T cells is essential for effective Type 2 immunity and resistance to T. muris infection.

bioRxiv · Nov 30, 2020Immunology