Author

J. Egea

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Perramon-Guell· 2 shared A. Yeramian· 2 shared G. Altes· 2 shared M. Encinas· 2 shared R. Navaridas· 2 shared X. Dolcet· 2 shared X. Matias-Guiu· 2 shared A. Bogdanova· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

A. Perramon-Guell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multiple endocrine defects in adult-onset Sprouty1/2/4 triple knockout mice

G. Altes, A. Olomi, A. Perramon-Guell, S. Hernandez, A. Casanovas, A. Perez, J. M. Diaz-Tocados, J. M. Valdivielso, C. Megino, R. Navaridas, X. Matias-Guiu, O. D. Klein, J. Egea, X. Dolcet, A. Yeramian, M. Encinas

This study investigates adult-onset Sprouty1/2/4 triple knockout mice, revealing endocrine defects without increased tumor incidence.

bioRxiv · Apr 18, 2024Physiology

In vivo intra-uterine delivery of TAT-fused Cre recombinase and CRISPR/Cas9 editing unveil histopathology of Pten/p53-deficient endometrial cancers.

R. Navaridas, M. Vidal-Sabanes, A. Ruiz-Mitjana, G. Altes, A. Perramon-Guell, A. Yeramian, J. Egea, M. Encinas, S. Gatius, X. Matias-Guiu, X. Dolcet

This study shows that simultaneous deletion of Pten and p53 in endometrial epithelial cells leads to epithelial to mesenchymal transition and the formation of uterine carcinosarcomas in vivo.

bioRxiv · Jun 8, 2023 · PreprintPathology

Mitochondrial Na+ controls oxidative phosphorylation and hypoxic redox signalling

P. Hernansanz-Agustin, C. Choya-Foces, S. Carregal-Romero, E. Ramos, T. Oliva, T. Villa-Pina, L. Moreno, A. Izquierdo-Alvarez, J. D. Cabrera-Garcia, A. Cortes, A. V. Lechuga-Vieco, P. Jadiya, E. Navarro, E. Parada, A. Palomino-Antolin, , A. Martinez-Ruiz

This study shows that mitochondrial Na+ acts as a second messenger regulating OXPHOS and ROS production through interactions with phospholipids during hypoxia.

bioRxiv · Oct 31, 2019Biochemistry