J. Luo

The paper describes a pipeline for generating 3D molecular atlases of human kidney biopsies using multi-OMICS and imaging technologies, emphasizing quality control and reproducibility across institutions.

This study identifies miR-1 as a conserved microRNA in ticks that prolongs engorgement time and is differentially expressed across developmental stages.

This paper develops a nanobody platform for drug delivery, showing improved pharmacokinetics and therapeutic efficacy of NbHSA conjugates.

This study identifies Na2CO3-responsive proteins and phosphoproteins in alkaligrass, revealing mechanisms for photosynthesis and ROS homeostasis under alkali-salinity stress.

The paper identifies Lem27 as a bacterial deubiquitinase that regulates ubiquitin dynamics on Legionella phagosomes by counteracting E3 ligases.

This study shows JNK signaling promotes dental papilla cell polarization by regulating polarity-related genes and RhoA activity during tooth development.

This study shows BET bromodomain inhibitors cause DNA damage by inducing R-loops and transcription-replication conflicts through impaired transcription elongation.

This study shows that hexaploidization in wheat enhances genetic recombination of the ancestral diploid genome, increasing evolutionary potential and aiding wheat's global spread.

This study investigates how Ralstonia solanacearum uses effector proteins to elicit and suppress plant immunity in Nicotiana benthamiana.

This paper characterizes an ammonia-tolerant ammonia-oxidizing archaeon from vegetable soil, identifying genomic and physiological mechanisms underlying its high ammonia tolerance.

This study shows ghrelin prevents white adipose tissue inflammation and atrophy in cancer cachexia, but GHSR-1a is only needed for its appetite-stimulating effect.

This study identifies lncRNA AVAN as a positive regulator of antiviral innate immunity by interacting with TRIM25 and enhancing FOXO3a transcription.

This study engineered Acinetobacter baylyi ADP1 to produce wax esters under nitrogen-rich conditions by modifying central carbon metabolism and overexpressing a key enzyme, achieving high yield and titer.

This study evaluates the toxicity of Chinese herbal toothpaste and its extracts on red imported fire ants, finding significant mortality rates and suggesting potential for bait use in pest control.

The paper evaluates sand dune restoration methods on the Zoige Plateau, finding that sandbag and wicker with seeding improved soil conditions more than seeding alone.

The paper proposes a deep learning approach for clutter suppression in ultrasound imaging, showing improved image quality and contrast compared to existing methods.

The paper demonstrates the production of 1-undecene from lignin-derived ferulate using a synthetic metabolic pathway in Acinetobacter baylyi ADP1.

The paper identifies type-2 CD8+ T cells (Tc2) enriched in severe eosinophilic asthma and shows PGD2 and LTE4 drive their recruitment and activation, contributing to eosinophilia.

The paper improves low-resolution crystallographic structures by incorporating homology-derived hydrogen bond restraints.