S. Ouyang

CRISPR-repressed toxin-antitoxin provides population-level immunity against diverse anti-CRISPR elements

The paper identifies a CRISPR-repressed toxin that provides population-level immunity against diverse anti-CRISPR elements by expelling them through abortive infection-like effects.

The soil emergence-related transcription factor PIF3 regulates root penetration by interacting with the receptor kinase FER

This study shows that PIF3, a transcription factor, regulates root penetration in Arabidopsis by interacting with FER, a receptor kinase, and modulating mechanosensitive ion channels and root cap cell sloughing.

Botrytis cinerea small RNAs are associated with tomato AGO1 and silence tomato defense-related target genes supporting cross-kingdom RNAi

The paper reanalyzes existing data to show cross-kingdom RNAi between Botrytis cinerea and tomato, contradicting a previous study.

Chemoenzymatic Measurement of Cell-surface Glycan in Single-cell Multiomics: LacNAc as an Example

The paper introduces a chemoenzymatic method to detect cell-surface glycan in single-cell multiomics, showing increased LacNAc in activated CD8+ T cells and its correlation with glycolytic activity.

Wounding promotes root regeneration through a cell wall integrity sensor, the receptor kinase FERONIA

The paper identifies RALF33-FER as an early signaling module between wounding and root regeneration, interacting with TPL/TPRs to regulate regeneration-related genes.

An integrative structural model of the full-length gp16 ATPase in bacteriophage phi29 DNA packaging motor

This study reports the crystal structure of gp16-CTD and simulations of the full-length gp16, revealing its role in dsDNA packaging through interactions with pRNA and dynamic domain interplay, refining the inchworm-revolution model.

Genetic analysis of the septal peptidoglycan synthase FtsWI complex supports a conserved activation mechanism for SEDS-bPBP complexes

The paper identifies mutations in FtsW and FtsI that reveal the activation mechanism of the SEDS-bPBP complex FtsWI, showing it relies on an interaction between FtsW's ECL4 and FtsI's pedestal domain.

Cryo-electron microscopy structure of the SADS-CoV spike glycoprotein provides insights into an evolution of unique coronavirus spike proteins

This study reports the cryo-EM structure of the SADS-CoV spike protein, revealing its unique structural features and evolutionary insights.

Evolutionary arms race between virus and host drives genetic diversity in bat SARS related coronavirus spike genes

This study shows that evolutionary arms race between bat SARSr-CoV spike proteins and ACE2 drives genetic diversity, with SARSr-CoV spike proteins showing higher binding affinity to human ACE2 than bat ACE2.

Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes

The paper identifies Lem27 as a bacterial deubiquitinase that regulates ubiquitin dynamics on Legionella phagosomes by counteracting E3 ligases.

Evidence of the Recombinant Origin and Ongoing Mutations in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

This study identifies SARS-CoV-2 as a recombinant virus of bat and pangolin coronaviruses and reports ongoing mutations in its genome.

Molecular basis of ubiquitination catalyzed by the bacterial transglutaminase MavC

This study determines the structure of the MavC-UBE2N-Ub complex, revealing the mechanism of MavC's transglutaminase and deamidase activities and its opposing activity to MvcA.