Author

J. Neidleman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:flow cytometry· 6 Organism:human· 6 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

N. R. Roan· 5 shared X. Luo· 5 shared G. Xie· 4 shared T. Ma· 4 shared W. C. Greene· 4 shared J. Frouard· 3 shared M. McGregor· 3 shared R. Hoh· 3 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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5 shared papersImmunology

N. R. Roan

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Author profile →

6 papers

Recent·Most cited

Long COVID manifests with T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2

K. Yin, M. J. Peluso, X. Luo, R. Thomas, M.-G. Shin, J. Neidleman, A. Andrew, K. Young, T. Ma, R. Hoh, K. Anglin, B. Huang, U. Argueta, M. Lopez, D. Valdivieso, , N. R. Roan

This study identifies T cell dysregulation, inflammation, and mis-coordinated adaptive immune responses in Long COVID patients compared to non-LC individuals.

bioRxiv · Feb 9, 2023Immunology

Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells from HIV+ Controllers and Non-Controllers

A. F. George, X. Luo, J. Neidleman, R. Hoh, P. Vohra, R. Thomas, M.-G. Shin, M. J. Lee, C. A. Blish, S. G. Deeks, W. C. Greene, S. A. Lee, N. R. Roan

This study compares T and NK cell phenotypes in blood and lymph nodes of HIV+ controllers and ART-treated individuals, finding distinct cellular features in lymphoid tissues.

bioRxiv · Oct 27, 2021 · PreprintImmunology

mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status

J. Neidleman, X. Luo, M. McGregor, G. Xie, V. Murray, W. C. Greene, S. A. Lee, N. R. Roan

eLife · Oct 12, 2021Peer-reviewedImmunology

Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence

T. Ma, H. Ryu, M. McGregor, B. Babcock, J. Neidleman, G. Xie, A. F. George, J. Frouard, V. Murray, G. Gill, E. Ghosn, E. Newell, S. Lee, N. Roan

The paper characterizes the long-term differentiation of SARS-CoV-2-specific CD8+ T cells in convalescent donors, showing coordinated evolution with other immune components over six months.

bioRxiv · Apr 28, 2021Immunology

The Atlas of the In Vivo HIV CD4 T Cell Reservoir

J. Neidleman, X. Luo, J. Frouard, G. Xie, F. Hsiao, T. Ma, V. Morcilla, A. Lee, S. Telwatte, R. Thomas, W. Tamaki, B. Wheeler, R. Hoh, P. Vohra, J. Milush, , N. R. Roan

The paper develops a method to trace latently-infected HIV CD4 T cells to their original states using CyTOF, revealing the reservoir's conserved yet tissue-specific composition and enabling isolation of unstimulated latent cells.

bioRxiv · Jun 27, 2020Immunology

SARS-CoV-2-specific T cells exhibit unique features reflecting robust helper function, lack of terminal differentiation, and high proliferative potential

J. Neidleman, X. Luo, J. Frouard, G. Xie, G. Gill, E. S. Stein, M. McGregor, T. Ma, A. George, A. Kosters, W. C. Greene, J. Vasquez, E. Ghosn, S. Lee, N. R. Roan

The paper characterizes SARS-CoV-2-specific T cells in recovered patients, finding they exhibit robust helper function, reduced terminal differentiation, and high proliferative potential.

bioRxiv · Jun 8, 2020Immunology