Author

J. R. Huh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:metagenomics· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. S. Devlin· 2 shared C. Huttenhower· 2 shared D. Paik· 2 shared E. A. Franzosa· 2 shared L. Yao· 2 shared S. Bae· 2 shared Y. Zhang· 2 shared A. Fasano· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

A. S. Devlin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Sexually dimorphic placental responses to maternal SARS-CoV-2 infection

E. A. Bordt, L. L. Shook, C. Atyeo, K. M. Pullen, R. M. De Guzman, M.-C. Meinsohn, M. Chauvin, S. Fischinger, L. J. Yockey, K. James, R. Lima, L. M. Yonker, A. Fasano, S. Brigida, L. M. Bebell, , A. G. Edlow

The paper investigates sex differences in placental responses to maternal SARS-CoV-2 infection, finding sex-specific changes in interferon genes, Fc-receptor expression, and antibody transfer.

bioRxiv · Mar 29, 2021 · PreprintImmunology

Human gut bacteria produce TH17-modulating bile acid metabolites

D. Paik, L. Yao, Y. Zhang, S. Bae, G. D. D'Agostino, E. Kim, E. A. Franzosa, J. Avila-Pacheco, J. E. Bisanz, C. K. Rakowski, H. Vlamakis, R. J. Xavier, P. J. Turnbaugh, R. S. Longman, M. R. Krout, , A. S. Devlin

This study identifies human gut bacteria that produce TH17-modulating bile acid metabolites, showing reduced levels in IBD patients.

bioRxiv · Jan 8, 2021 · PreprintImmunology

A Bacterial Bile Acid Metabolite Modulates Treg Activity through the Nuclear Hormone Receptor NR4A1

W. Li, S. Hang, Y. Fang, S. Bae, Y. Zhang, G. Wang, M. D. McCurry, M. Bae, E. A. Franzosa, C. Huttenhower, L. Yao, A. S. Devlin, J. R. Huh

This study identifies a bacterial bile acid metabolite, isoalloLCA, that enhances Treg cell differentiation via NR4A1 and is reduced in inflammatory bowel disease patients.

bioRxiv · Jan 8, 2021Immunology

Gut-innervating nociceptor neurons protect against enteric infection by modulating the microbiota and Peyer’s patch microfold cells

N. Y. Lai, M. A. Musser, F. A. Pinho-Ribeiro, P. Baral, P. Ma, D. E. Potts, Z. Chen, D. Paik, S. Soualhi, H. Shi, A. Misra, K. Goldstein, K. N. Sivanathan, A. Jacobson, A. Wallrapp, , I. M. Chiu

This study shows gut-innervating nociceptors protect against Salmonella typhimurium infection by modulating microbiota and Peyer’s patch microfold cells.

bioRxiv · Mar 21, 2019 · PreprintImmunology