Author

S. Hang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Hsiao· 1 shared A. S. Devlin· 1 shared B. Bao· 1 shared B. Nelson· 1 shared C. Benoist· 1 shared C. Huttenhower· 1 shared C. Thompson· 1 shared D. Coronado· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

A. Hsiao

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3 papers

Recent·Most cited

Microbiome induced complement synthesized in the gut protects against enteric infections

M. Wu, W. Zheng, X. Song, B. Bao, Y. Wang, D. Ramanan, D. Yang, R. Liu, J. C. Macbeth, E. A. Do, W. A. Andrade, T. Yang, H.-S. Cho, F. S. Gazzaniga, M. Ilves, , D. L. Kasper

The paper shows gut microbiota regulate complement component 3 (C3) production in humans and mice, with intestinal C3 levels correlating with protection against enteric infections.

bioRxiv · Feb 2, 2023 · PreprintImmunology

A Bacterial Bile Acid Metabolite Modulates Treg Activity through the Nuclear Hormone Receptor NR4A1

W. Li, S. Hang, Y. Fang, S. Bae, Y. Zhang, G. Wang, M. D. McCurry, M. Bae, E. A. Franzosa, C. Huttenhower, L. Yao, A. S. Devlin, J. R. Huh

This study identifies a bacterial bile acid metabolite, isoalloLCA, that enhances Treg cell differentiation via NR4A1 and is reduced in inflammatory bowel disease patients.

bioRxiv · Jan 8, 2021Immunology

Bile acid metabolites control Th17 and Treg cell differentiation

S. Hang, D. Paik, S. Devlin, T. Jamma, J. Lu, S. Ha, B. Nelson, S. Kelly, L. Wu, Y. Zheng, F. Rastinejad, M. Krout, M. Fischbach, D. Littman, J. Huh

This study identifies two bile acid metabolites that regulate Th17 and Treg cell differentiation through distinct mechanisms, affecting immune balance in mice.

bioRxiv · Nov 8, 2018Immunology