Author

J. S. Debley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

L. M. Rich· 3 shared E. R. Vanderwall· 2 shared K. A. Barrow· 2 shared A. Barilli· 1 shared A. Sali· 1 shared B. T. Chait· 1 shared C. Fung· 1 shared C. Trapnell· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

L. M. Rich

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tuft cell-derived acetylcholine regulates epithelial fluid secretion

T. E. Billipp, C. Fung, L. M. Webeck, D. B. Sargent, M. B. Gologorsky, M. M. McDaniel, D. N. Kasal, J. W. McGinty, K. A. Barrow, L. M. Rich, A. Barilli, M. Sabat, J. S. Debley, R. Myers, M. R. Howitt, J. von Moltke

This study shows that tuft cell-derived acetylcholine in the intestine triggers immediate fluid secretion, distinct from its role in immune responses, and is involved in Type 2 inflammation and helminth clearance.

bioRxiv · Mar 17, 2023 · PreprintImmunology

Airway epithelial interferon response to SARS-CoV-2 is inferior to rhinovirus and heterologous rhinovirus infection suppresses SARS-CoV-2 replication

E. R. Vanderwall, K. A. Barrow, L. M. Rich, D. F. Read, C. Trapnell, O. Oghenemega, S. F. Ziegler, T. S. Hallstrand, M. P. White, J. S. Debley

The paper compares the IFN response to SARS-CoV-2 and HRV-16 in airway epithelial cells and shows that HRV-16 induces a stronger IFN response and reduces SARS-CoV-2 replication.

bioRxiv · Nov 20, 2021Immunology

Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2

F. D. Mast, P. C. Fridy, N. E. Ketaren, J. Wang, E. Y. Jacobs, J. P. Olivier, T. Sanyal, K. R. Molloy, F. Schmidt, M. Rutkowska, Y. Weisblum, L. M. Rich, E. R. Vanderwall, N. Dambrauskas, V. Vigdorovich, , M. P. Rout

This paper presents a large repertoire of high-affinity nanobodies against SARS-CoV-2 Spike protein with potent neutralization properties and resistance to viral variants.

bioRxiv · Apr 8, 2021Biochemistry