Author

J. T. Becker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

N. M. Sherer· 2 shared A. Barkhymer· 1 shared A. E. Bates· 1 shared A. M. Weiler· 1 shared A. Richardon· 1 shared A. S. Jaeger· 1 shared B. Benner· 1 shared B. E. Benner· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiochemistry

N. M. Sherer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Primary infection with Zika virus provides one-way heterologous protection against Spondweni virus infection in rhesus macaques

A. S. Jaeger, C. M. Crooks, A. M. Weiler, M. I. Bliss, S. L. Rybarczyk, A. Richardon, M. Einwalter, E. Peterson, S. Capuano, A. Barkhymer, J. T. Becker, J. T. Greene, T. S. Freedman, R. A. Langlois, T. C. Friedrich, M. T. Aliota

This study shows that ZIKV infection protects against SPONV in rhesus macaques, but not vice versa, suggesting one-way cross-protection between the viruses.

bioRxiv · Dec 16, 2022Microbiology

Gain-of-function assay for SARS-CoV-2 Mpro inhibition in living cells

S. A. Moghadasi, J. T. Becker, C. Belica, C. Wick, W. L. Brown, R. Harris

The paper develops a gain-of-function assay to measure SARS-CoV-2 Mpro inhibition in living cells, using eGFP fluorescence to quantify inhibitor potency and enable high-throughput drug testing.

bioRxiv · Nov 9, 2020 · PreprintMicrobiology

Identifying HIV-1 RNA splice variant protein interactomes using HyPR-MSSV

R. Knoener, E. Evans, J. T. Becker, M. Scalf, B. Benner, N. M. Sherer, L. M. Smith

This study identifies protein interactomes of HIV-1 RNA splice variants using HyPR-MSSV, revealing 212 differentially associated proteins and their roles in viral replication.

bioRxiv · Sep 15, 2020 · PreprintBiochemistry

HIV-1 RNA genomes initiate host protein packaging in the cytosol independently of Gag capsid proteins

J. T. Becker, E. L. Evans, B. E. Benner, S. L. Pritzl, L. E. Smith, A. E. Bates, N. M. Sherer

This study shows HIV-1 RNA interacts with APOBEC3G and MOV10 in the cytosol before Gag, and these interactions are critical for A3G packaging into virions.

bioRxiv · May 20, 2020 · PreprintCell Biology