Author

Jack D. Nothnagel

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3

Frequent Co-Authors

Alex C. KwaniD· 3 shared Ling-Xiao ShaoiD· 3 shared Neil K. SavaliaiD· 3 shared Pasha A. DavoudianiD· 3 shared Quan JiangiD· 3 shared Clara LiaoiD· 2 shared A. M. WeineriD· 1 shared Alicia CheiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Alex C. KwanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Psilocybin reshapes cortical inhibition through selective interneuron recruitment

Pasha A. Davoudian, Quan Jiang, Cory A. Knox, Neil K. Savalia, Ling-Xiao Shao, Joshua Wilson, A. M. Weiner, Catherine W Chong, Clara Liao, Jack D. Nothnagel, Takeshi Sakurai, Alex C. Kwan

This study shows psilocybin selectively affects GABAergic interneurons in the mouse medial frontal cortex, reducing somatostatin-expressing and increasing parvalbumin-expressing neuron activity.

bioRxiv · Apr 17, 2026 · PreprintNeuroscience

Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks

Quan Jiang, Ling-Xiao Shao, Shenqin Yao, Neil K. Savalia, Amelia D. Gilbert, Pasha A. Davoudian, Jack D. Nothnagel, Guilian Tian, Jacky Tin Shing Hung, H. M. Lai, Kevin Thomas Beier, Hongkui Zeng, Alex C. Kwan

This study shows psilocybin alters large-scale cortical network connectivity in mice by strengthening inputs from perceptual and medial regions and weakening cortico-cortical loops, dependent on drug-evoked spiking activity.

Cell · Dec 5, 2025Peer-reviewedNeuroscience

Pyramidal cell types and 5-HT2A receptors are essential for psilocybin's lasting drug action

Ling-Xiao Shao, Clara Liao, Pasha A. Davoudian, Neil K. Savalia, Quan Jiang, Cassandra Wojtasiewicz, Diran Tan, Jack D. Nothnagel, Rongjian Liu, Samuel C. Woodburn, Olesia M. Bilash, Hail Kim, Alicia Che, Alex C. Kwan

This study identifies specific pyramidal cell types and 5-HT2A receptors in the medial frontal cortex as essential for psilocybin's long-term therapeutic effects.

bioRxiv · Nov 2, 2024 · PreprintNeuroscience