Author

Dulcie A. Vousden

Hospital for Sick ChildrenORCID 0000-0002-9063-0174Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jason P. LerchiD· 4 shared Brian J. NiemaniD· 3 shared Darren FernandesiD· 2 shared Leigh Spencer NoakesiD· 2 shared Lily R. QiuiD· 2 shared Alexander von Friesen· 1 shared Andrew Tu· 1 shared Anthony Christopher VernoniD· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersNeuroscience

Jason P. LerchORCID

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Author profile →

4 papers

Recent·Most cited

A unique cerebellar pattern of microglia activation in a mousemodel of encephalopathy of prematurity

Luisa Klein, Juliette Van Steenwinckel, Bobbi Fleiss, Till Scheuer, Christoph Bührer, Valérie Faivre, Sophie Lemoine, Corinne Blugeon, Leslie Schwendimann, Zsolt Csaba, Cindy Bokobza, Dulcie A. Vousden, Jason P. Lerch, Anthony Christopher Vernon, Pierre Gressèns, Thomas Schmitz

This study investigates the effects of perinatal inflammation on cerebellar development in a mouse model of encephalopathy of prematurity, finding unique microglia activation and type I interferon signaling dysregulation in the cerebellum.

Glia · May 17, 2022Peer-reviewedNeuroscience

Mouse models of immune dysfunction: Their neuroanatomical differences reflect their anxiety-behavioural phenotype

Darren Fernandes, Shoshana Spring, Christina Corre, Andrew Tu, Lily R. Qiu, Christopher F. Hammill, Dulcie A. Vousden, T. Leigh Spencer Noakes, Brian J. Nieman, Dawn M. E. Bowdish, Jane Allyson Foster, Mark R. Palmert, Jason P. Lerch

The paper uses MRI and Bayesian hierarchical modeling to show that immune dysfunction in mice affects specific brain regions and correlates with anxiety-like behaviors.

Molecular Psychiatry · Apr 14, 2022Peer-reviewedNeuroscience

Genetic and behavioural requirements for structural brain plasticity

Dulcie A. Vousden, Alexander von Friesen, Xianglan Wen, Lily R. Qiu, Nicholas O’Toole, Benjamin C Darwin, Leigh Spencer Noakes, Rylan Allemang-Grand, Josie C. Diorio, Paul W. Frankland, Sheena A. Josselyn, Brian J. Nieman, Michael J. Meaney, Tieyuan Zhang, Jason P. Lerch

The paper investigates how environmental enrichment affects brain volume in mice and identifies molecular processes involved, showing CREB is not required for these changes.

bioRxiv · Oct 3, 2018 · PreprintNeuroscience

Structural covariance of brain region volumes is associated with both structural connectivity and transcriptomic similarity

Yohan Yee, Darren Fernandes, Leon French, Jacob Ellegood, Lindsay S. Cahill, Dulcie A. Vousden, Leigh Spencer Noakes, Jan Scholz, Matthijs C. van Eede, Brian J. Nieman, John G. Sled, Jason P. Lerch

The paper investigates structural covariance in mouse brain regions, finding that it is explained by distance, transcriptomic similarity, and connectivity, with varying contributions across brain areas.

NeuroImage · May 18, 2018Peer-reviewedNeuroscience