Author

K. K.-H. Chik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

H. Chu· 3 shared K. K.-W. To· 3 shared K.-Y. Yuen· 3 shared C. C.-S. Chan· 2 shared C. C.-Y. Chan· 2 shared D. D. Ho· 2 shared H. Chen· 2 shared J. F.-W. Chan· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

H. Chu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The SARS-CoV-2 Omicron (B.1.1.529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster model

S. Yuan, Z.-W. Ye, R. Liang, K. Tang, A. J. Zhang, G. Lu, C. P. Ong, V. K.-M. Poon, C. C.-S. Chan, B. W. Y. Mok, Z. Qin, Y. Xie, H. Sun, J. O.-L. Tsang, T. T.-T. Yuen, , J. F. W. Chan

The study compares the pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron and Delta variants in golden Syrian hamsters, finding Omicron less pathogenic but more transmissible and capable of outcompeting Delta under immune pressure.

bioRxiv · Jan 12, 2022 · PreprintMicrobiology

Striking Antibody Evasion Manifested by the Omicron Variant of SARS-CoV-2

L. Liu, S. Iketani, Y. Guo, J. F.-W. Chan, M. Wang, L. Liu, Y. Luo, H. Chu, Y. Huang, M. S. Nair, J. Yu, K. K.-H. Chik, T. T.-T. Yuen, C. Yoon, K. K.-W. To, , D. D. Ho

This study shows that the Omicron variant of SARS-CoV-2 is highly resistant to neutralization by convalescent serum and vaccines, and many monoclonal antibodies.

bioRxiv · Dec 14, 2021Microbiology

SARS-CoV-2 hijacks neutralizing dimeric IgA for enhanced nasal infection and injury

B. Zhou, R. Zhou, J. F.-W. Chan, J. Zeng, Q. Zhang, S. Yuan, L. Liu, R. Robinot, S. Shan, J. Ge, H. Y.-H. Kwong, D. Zhou, H. Xu, C. C.-S. Chan, V. K.-M. Poon, , Z. Chen

This study shows that dimeric IgA antibodies can enhance SARS-CoV-2 nasal infection and injury in Syrian hamsters by engaging CD209 as an alternative receptor.

bioRxiv · Oct 5, 2021 · PreprintMicrobiology